Neuroprognostic accuracy of blood biomarkers for post-cardiac arrest patients: A systematic review and meta-analysis

CH Wang, WT Chang, KI Su, CH Huang, MS Tsai… - Resuscitation, 2020 - Elsevier
Aim To summarise and compare the prognostic accuracy of the blood biomarkers of brain
injury, including NSE and S-100B, for neurological outcomes in adult post-cardiac arrest …

Serum neuron-specific enolase thresholds for predicting postcardiac arrest outcome: a systematic review and meta-analysis

K Sharma, M John, S Zhang, G Gronseth - Neurology, 2022 - AAN Enterprises
Background and Objectives To determine thresholds of serum neuron-specific enolase
(NSE) for prediction of poor outcome after cardiac arrest with> 95% specificity using a …

The neuron specific enolase (NSE) ratio offers benefits over absolute value thresholds in post-cardiac arrest coma prognosis

HM Chung-Esaki, G Mui, M Mlynash, I Eyngorn… - Journal of Clinical …, 2018 - Elsevier
Introduction Serum neuron-specific enolase (NSE) levels have been shown to correlate with
neurologic outcome in comatose survivors of cardiac arrest but use of absolute NSE …

Neuron-specific enolase and long-term neurological outcome after OHCA–a validation study

EL Östlund, H Levin, N Nielsen, A Frigyesi, A Lybeck - Resuscitation, 2021 - Elsevier
Aims To investigate what NSE levels predict long-term neurological prognosis at 24, 48 and
72 hours after ROSC in a cohort of out-of-hospital cardiac arrest and to validate previously …

Blood–brain barrier disruption as a cause of various serum neuron-specific enolase cut-off values for neurological prognosis in cardiac arrest patients

C Kang, Y You, HJ Ahn, JS Park, W Jeong, JH Min… - Scientific Reports, 2022 - nature.com
We compared the cut-off and prognostic value of serum neuron-specific enolase (NSE)
between groups with and without severe blood–brain barrier (BBB) disruption to reveal that …

[HTML][HTML] Prognostic utility of neuroinjury biomarkers in post out-of-hospital cardiac arrest (OHCA) patient management

SS Gul, KW Huesgen, KK Wang, K Mark, JA Tyndall - Medical hypotheses, 2017 - Elsevier
Despite aggressive intervention, patients who survive an out-of-hospital cardiac arrest
(OHCA) generally have very poor prognoses, with nationwide survival rates of …

Correlation between initial serum levels of lactate after return of spontaneous circulation and survival and neurological outcomes in patients who undergo therapeutic …

DH Lee, IS Cho, SH Lee, YI Min, JH Min, SH Kim… - Resuscitation, 2015 - Elsevier
Objectives We analysed the relationship between serum levels of lactate within 1 h of return
of spontaneous circulation (ROSC) and survival and neurological outcomes in patients who …

Biomarkers as predictors of outcome after cardiac arrest

S Scolletta, K Donadello, C Santonocito… - Expert review of …, 2012 - Taylor & Francis
Cardiac arrest (CA) is a major health and economic problem. Management of patients
resuscitated from CA is challenging for clinicians, and the mortality rate of those who …

[HTML][HTML] Therapeutic hypothermia after cardiac arrest: outcome predictors

RN Leão, P Ávila, R Cavaco, N Germano… - Revista Brasileira de …, 2015 - SciELO Brasil
Objetivo: A determinação do prognóstico de pacientes em coma após parada cardíaca tem
implicações clínicas, éticas e sociais. Exame neurológico, marcadores de imagem e …

Biomarkers in traumatic brain injury

R Sharma, DT Laskowitz - Current neurology and neuroscience reports, 2012 - Springer
Traumatic brain injury (TBI) is a common cause of neurological morbidity globally, and
neurologic sequelae may occur even in the setting of mild injury. At present, the tools that …