Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Microfluidic-based technologies for CTC isolation: a review of 10 years of intense efforts towards liquid biopsy

L Descamps, D Le Roy, AL Deman - International Journal of Molecular …, 2022 - mdpi.com
The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

Scalable COVID-19 detection enabled by lab-on-chip biosensors

C Tymm, J Zhou, A Tadimety, A Burklund… - Cellular and molecular …, 2020 - Springer
Introduction The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need
for rapid, accurate, and point-of-care diagnostic testing. As of now, there is not enough …

Role of exosomes and exosomal microRNAs in cancer

N Dilsiz - Future science OA, 2020 - Taylor & Francis
A growing body of evidence indicates that exosomes play a critical role in the cell–cell
communication process. Exosomes are biological nanoparticles with an average diameter of …

Point-of-care cancer diagnostic devices: From academic research to clinical translation

L Syedmoradi, ML Norton, K Omidfar - Talanta, 2021 - Elsevier
Early and timely diagnosis of cancer plays a decisive role in appropriate treatment and
improves clinical outcomes, improving public health. Significant advances in biosensor …

CRISPR-Cas13 system as a promising and versatile tool for cancer diagnosis, therapy, and research

F Palaz, AK Kalkan, O Can, AN Demir… - ACS Synthetic …, 2021 - ACS Publications
Over the past decades, significant progress has been made in targeted cancer therapy. In
precision oncology, molecular profiling of cancer patients enables the use of targeted cancer …

High‐performance nucleic acid sensors for liquid biopsy applications

J Das, SO Kelley - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Circulating tumour nucleic acids (ctNAs) are released from tumours cells and can be
detected in blood samples, providing a way to track tumors without requiring a tissue …

Exosomes as powerful engines in cancer: isolation, characterization and detection techniques

MG Saad, H Beyenal, WJ Dong - Biosensors, 2021 - mdpi.com
Exosomes, powerful extracellular nanovesicles released from almost all types of living cells,
are considered the communication engines (messengers) that control and reprogram …

Updates on clinical use of liquid biopsy in colorectal cancer screening, diagnosis, follow-up, and treatment guidance

O Mazouji, A Ouhajjou, R Incitti… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide, being the third most
diagnosed in the world and the second deadliest. Solid biopsy provides an essential guide …

SARS-CoV-2-on-chip for long COVID management

J Cherusseri, CM Savio, M Khalid, V Chaudhary… - Biosensors, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a “wicked
evil” in this century due to its extended progression and huge human mortalities. Although …