Liposomes used as a vaccine adjuvant-delivery system: From basics to clinical immunization

N Wang, M Chen, T Wang - Journal of Controlled Release, 2019 - Elsevier
Liposomes are widely utilized as a carrier to improve therapeutic efficacy of agents thanks to
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …

Engineering synthetic vaccines using cues from natural immunity

DJ Irvine, MA Swartz, GL Szeto - Nature materials, 2013 - nature.com
Vaccines aim to protect against or treat diseases through manipulation of the immune
response, promoting either immunity or tolerance. In the former case, vaccines generate …

Modulating antibacterial immunity via bacterial membrane-coated nanoparticles

W Gao, RH Fang, S Thamphiwatana, BT Luk, J Li… - Nano …, 2015 - ACS Publications
Synthetic nanoparticles coated with cellular membranes have been increasingly explored to
harness natural cell functions toward the development of novel therapeutic strategies …

Immunological mechanisms of vaccination

B Pulendran, R Ahmed - Nature immunology, 2011 - nature.com
Vaccines represent one of the greatest triumphs of modern medicine. Despite the common
origins of vaccinology and immunology more than 200 years ago, the two disciplines have …

Nanoparticle approaches against bacterial infections

W Gao, S Thamphiwatana… - Wiley interdisciplinary …, 2014 - Wiley Online Library
Despite the wide success of antibiotics, the treatment of bacterial infections still faces
significant challenges, particularly the emergence of antibiotic resistance. As a result …

From vaccines to memory and back

F Sallusto, A Lanzavecchia, K Araki, R Ahmed - Immunity, 2010 - cell.com
Vaccines work by eliciting an immune response and consequent immunological memory
that mediates protection from infection or disease. Recently, new methods have been …

[PDF][PDF] A powerful CD8+ T-cell stimulating D-tetra-peptide hydrogel as a very promising vaccine adjuvant

Z Luo, Q Wu, C Yang, H Wang, T He, Y Wang… - Adv. Mater, 2017 - researchgate.net
DOI: 10.1002/adma. 201601776 oil-in-water emulsion MF59) can only stimulate a humoral
immune response without eliciting a cellular immune response.[6] In order to develop …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype

SL Demento, W Cui, JM Criscione, E Stern, J Tulipan… - Biomaterials, 2012 - Elsevier
Particulate vaccines are emerging promising technologies for the creation of tunable
prophylactics against a wide variety of conditions. Vesicular and solid biodegradable …

Accelerating next-generation vaccine development for global disease prevention

WC Koff, DR Burton, PR Johnson, BD Walker, CR King… - Science, 2013 - science.org
Background Vaccines have provided some of the greatest successes in the history of
medicine, including the eradication of smallpox, the near eradication of polio, and the …