Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer

KA Preethi, SC Selvakumar, K Ross, S Jayaraman… - Molecular Cancer, 2022 - Springer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …

Liquid biopsy as a tool for the diagnosis, treatment, and monitoring of breast cancer

AJA Freitas, RL Causin, MB Varuzza, S Calfa… - International journal of …, 2022 - mdpi.com
Breast cancer (BC) is a highly heterogeneous disease. The treatment of BC is complicated
owing to intratumoral complexity. Tissue biopsy and immunohistochemistry are the current …

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Exosomes as emerging drug delivery and diagnostic modality for breast cancer: recent advances in isolation and application

DN Kumar, A Chaudhuri, F Aqil, D Dehari, R Munagala… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is considered the second most occurring cancer after lung
cancer globally. The treatment for breast cancer includes surgery, radiation, chemotherapy …

[HTML][HTML] Current advances in prognostic and diagnostic biomarkers for solid cancers: Detection techniques and future challenges

M Pal, T Muinao, HPD Boruah, N Mahindroo - Biomedicine & …, 2022 - Elsevier
Solid cancers are one of the leading causes of cancer related deaths, characterized by rapid
growth of tumour, and local and distant metastases. Current advances on multimodality care …

Current status of circulating tumor cells, circulating tumor DNA, and exosomes in breast cancer liquid biopsies

M Tellez-Gabriel, E Knutsen, M Perander - International Journal of …, 2020 - mdpi.com
Breast cancer is the most common cancer among women worldwide. Although the five-, ten-
and fifteen-year survival rates are good for breast cancer patients diagnosed with early …

Tumor-derived exosomal non-coding RNAs: the emerging mechanisms and potential clinical applications in breast cancer

Y Yi, M Wu, H Zeng, W Hu, C Zhao, M Xiong… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BC) is the most frequent malignancy and is ranking the leading cause of
cancer-related death among women worldwide. At present, BC is still an intricate challenge …