The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity

IG Ovsyannikova, IH Haralambieva… - Immunological …, 2020 - Wiley Online Library
This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …

COVID-19 and SARS-CoV-2. Modeling the present, looking at the future

E Estrada - Physics reports, 2020 - Elsevier
Abstract Since December 2019 the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) has produced an outbreak of pulmonary disease which has soon become a …

Rubella

N Lambert, P Strebel, W Orenstein, J Icenogle… - The Lancet, 2015 - thelancet.com
Rubella remains an important pathogen worldwide, with roughly 100 000 cases of
congenital rubella syndrome estimated to occur every year. Rubella-containing vaccine is …

Vaccines, adjuvants and autoimmunity

LE Guimarães, B Baker, C Perricone… - Pharmacological …, 2015 - Elsevier
Vaccines and autoimmunity are linked fields. Vaccine efficacy is based on whether host
immune response against an antigen can elicit a memory T-cell response over time …

Personalized vaccinology: a review

GA Poland, IG Ovsyannikova, RB Kennedy - Vaccine, 2018 - Elsevier
At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …

[HTML][HTML] Immune response and molecular mechanisms of cardiovascular adverse effects of spike proteins from SARS-CoV-2 and mRNA vaccines

P Bellavite, A Ferraresi, C Isidoro - Biomedicines, 2023 - mdpi.com
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus responsible for the
COVID-19 disease) uses the Spike proteins of its envelope for infecting target cells …

[HTML][HTML] Modeling influenza virus infection: a roadmap for influenza research

A Boianelli, VK Nguyen, T Ebensen, K Schulze, E Wilk… - Viruses, 2015 - mdpi.com
Influenza A virus (IAV) infection represents a global threat causing seasonal outbreaks and
pandemics. Additionally, secondary bacterial infections, caused mainly by Streptococcus …

[HTML][HTML] Current challenges in vaccinology

RB Kennedy, IG Ovsyannikova, P Palese… - Frontiers in …, 2020 - frontiersin.org
The development of vaccines, which prime the immune system to respond to future
infections, has led to global declines in morbidity and mortality from dreadful infectious …

[HTML][HTML] Sex differences in older adults' immune responses to seasonal influenza vaccination

EA Voigt, IG Ovsyannikova, RB Kennedy… - Frontiers in …, 2019 - frontiersin.org
Background: Sex differences in immune responses to influenza vaccine may impact efficacy
across populations. Methods: In a cohort of 138 older adults (50–74 years old), we …

[HTML][HTML] The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what …

G Morris, BK Puri, RE Frye - Metabolic brain disease, 2017 - Springer
The conceptualisation of autistic spectrum disorder and Alzheimer's disease has undergone
something of a paradigm shift in recent years and rather than being viewed as single …