Стабильность генома является неотъемлемым свойством всех живых организмов (Jeggo et al., 2016). Ее качественной составляющей является последовательность …
RR Salakhov, AV Ponasenko - Complex Issues of Cardiovascular …, 2019 - nii-kpssz.com
Human telomere length shortens with aging and limits the number of cell divisions (Hayflick limit). This phenomenon is believed to be an evolutionary compromise to prevent the risk of …
Genome instability represents one of the leading forces driving the onset and development of cancer. It arises as a consequence of the combined effect of DNA damage and errors …
V Vymetalkova, L Vodickova, J Buchancova, R Kumar - academia.edu
Nonspecific chromosomal aberrations (CAs) are analyzed by microscopic scoring of metaphase nuclei and they include fragmented, missing, or fused chromosomal segments …
LINE-1 is an autonomous non-LTR retrotransposon in mammalian genomes and encodes ORF1P and ORF2P. ORF2P has been clearly identified as the enzyme supplier needed in …
Epigenetic changes, including DNA methylation, microRNA expression and histone modification, are heritable and stable alterations in regulation of gene transcription …
K Hemminki, R Sivaramakrishna… - Genes …, 2015 - Wiley Online Library
Nonspecific chromosomal aberrations (CAs) are analyzed by microscopic scoring of metaphase nuclei and they include fragmented, missing, or fused chromosomal segments …