Epigenetics functions as a bridge between host genetic & environmental factors, aiding in
human health and diseases. Many immune-related diseases, including infectious and …

Purpose The COVID-19 pandemic caused by the novel Severe Acute Respiratory Syndrome
Corona Virus 2 (SARS-CoV-2) has put the world in a medical crisis for the past three years; …

Bronchiolitis is the most common lower respiratory infection in infants, yet its pathobiology
remains unclear. Here we present blood DNA methylation data from 625 infants hospitalized …

Background Changes in cell-type composition of tissues are associated with a wide range of
diseases and environmental risk factors and may be causally implicated in disease …

DNA methylation clocks can accurately estimate chronological age and, to some extent, also
biological age, yet the process by which age-associated DNA methylation (DNAm) changes …

Background Microbial infection is accompanied by remodeling of the host transcriptome.
Involvement of A-to-I RNA editing has been reported during viral infection but remains to be …

The cumulative number of stem cell divisions in a tissue, known as mitotic age, is thought to
be a major determinant of cancer-risk. Somatic mutational and DNA methylation (DNAm) …

Background: Different severities of coronavirus disease 2019 (COVID-19) cause different
levels of respiratory symptoms and systemic inflammation. DNA methylation, a heritable …

Patients infected with SARS-CoV-2 at various severities have different clinical
manifestations and treatments. Mild or moderate patients usually recover with conventional …

There is abundant epidemiological data indicating that the incidence of severe cases of
coronavirus disease (COVID-19) is significantly higher in males than females worldwide …