Recent findings have provided a molecular basis for the combined contributions of
multifaceted risk factors for the onset of multiple sclerosis (MS). MS appears to start as a …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by focal or diffuse inflammation, demyelination, axonal loss and …

It has been 200 years since Parkinson's disease (PD) was first described, yet many aspects
of its etiopathogenesis remain unclear. PD is a progressive and complex neurodegenerative …

Malignancies and diseases of various genetic origins can be diagnosed and classified with
microarray data. There are many obstacles to overcome due to the large size of the gene …

Cigarette smoking is the most prominent significant cause of death and morbidity. It is
recognised as a risk factor for a number of immune mediated, inflammatory diseases …

Epigenetics connects genetic and environmental factors: it includes DNA methylation,
histone post‐translational modifications and the regulation of chromatin accessibility by non …

Current clinical experience with immunomodulatory agents and monoclonal antibodies in
principle has established the benefit of depleting lymphocytic populations in relapsing …

Ischemic stroke (IS) is a major cause of death and disability, despite early intervention.
Thrombo-inflammation, the inflammatory process triggered by ischemia, is a concept that …

Amyotrophic lateral sclerosis (ALS) is a serious neurodegenerative disease that affects
motor neurons and leads to death within 2 to 3 years after the first symptoms manifest …

Objectives To validate in an ethnically homogeneous Greek multiple sclerosis (MS) cohort,
genetic risk factors for the disease, identified through a number of previous multi-ethnic …