Targeting epigenetics: a novel promise for Alzheimer's disease treatment
D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing Research Reviews, 2023 - Elsevier
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
Age-related changes in sperm DNA methylation and their forensic and clinical implications
L Kotková, J Drábek - Epigenomics, 2023 - Taylor & Francis
As a link between a stable genome and a dynamic environment, epigenetics is a promising
tool for mapping age-related changes in human DNA. Methylated cytosine changes at …
tool for mapping age-related changes in human DNA. Methylated cytosine changes at …
[HTML][HTML] Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
Aging clocks, built from comprehensive molecular data, have emerged as promising tools in
medicine, forensics, and ecological research. However, few studies have compared the …
medicine, forensics, and ecological research. However, few studies have compared the …
Improved age estimation from semen using sperm-specific age-related CpG markers
C Xiao, Y Li, M Chen, S Yi, D Huang - Forensic Science International …, 2023 - Elsevier
Accurate age estimation from semen has the potential to greatly narrow the pool of
unidentified suspects in sexual assault investigations. However, previous efforts utilizing …
unidentified suspects in sexual assault investigations. However, previous efforts utilizing …
Development and comparison of forensic interval age prediction models by statistical and machine learning methods based on the methylation rates of ELOVL2 in …
T Yamagishi, W Sakurai, K Watanabe… - Forensic Science …, 2024 - Elsevier
Age estimation can be useful information for narrowing down candidates of unidentified
donors in criminal investigations. Various age estimation models based on DNA methylation …
donors in criminal investigations. Various age estimation models based on DNA methylation …
ELOVL2‐methylation and renal and cardiovascular event in patients with chronic kidney disease
R Obeid, P Rickens, GH Heine… - European Journal of …, 2023 - Wiley Online Library
Abstract Background Methylation of the Elongation Of Very Long Chain Fatty Acids‐Like 2
(ELOVL2) gene promoter may predict premature ageing and cardiovascular risk. Methods …
(ELOVL2) gene promoter may predict premature ageing and cardiovascular risk. Methods …
[HTML][HTML] Predicting age from blood by droplet digital PCR using a set of three DNA methylation markers
HC Dias, L Manco - Forensic Science International, 2024 - Elsevier
Abstract Evaluation of DNA methylation (DNAm) patterns is a promising tool for age
estimation. The duplex droplet digital PCR (ddPCR) method has been recently investigated …
estimation. The duplex droplet digital PCR (ddPCR) method has been recently investigated …
DNA methylation of ELOVL2 gene as an epigenetic marker of age among Egyptian population
NM El-Shishtawy, FM El Marzouky… - Egyptian Journal of …, 2024 - Springer
Background Cellular and molecular changes occur during aging, decreasing organ function.
The aging process was measured by several biomarkers, including DNA methylation …
The aging process was measured by several biomarkers, including DNA methylation …
ComputAgeBench: Epigenetic Aging Clocks Benchmark
D Kriukov, E Efimov, EA Kuzmina, EE Khrameeva… - bioRxiv, 2024 - biorxiv.org
The success of clinical trials of longevity drugs relies heavily on identifying integrative health
and aging biomarkers, such as biological age. Epigenetic aging clocks predict the biological …
and aging biomarkers, such as biological age. Epigenetic aging clocks predict the biological …