Studying the interaction of drug/ligand with serum albumin

S Siddiqui, F Ameen, S ur Rehman, T Sarwar… - Journal of Molecular …, 2021 - Elsevier
The interaction between proteins and drugs/ligands has been explored thoroughly over the
past years. Numerous spectroscopic and in silico tools are employed to decipher the binding …

Biophysical insight into the binding mechanism of doxofylline to bovine serum albumin: An in vitro and in silico approach

S Siddiqui, F Ameen, T Kausar, SM Nayeem… - … Acta Part A: Molecular …, 2021 - Elsevier
Insight into the mechanistic binding of bovine serum albumin (BSA) with doxofylline can
layout pivotal enlightenment with relevance to pharmacokinetics and pharmacodynamics …

Investigating the mechanism of binding of nalidixic acid with deoxyribonucleic acid and serum albumin: A biophysical and molecular docking approaches

S Siddiqui, A Mujeeb, F Ameen, HM Ishqi… - Journal of …, 2021 - Taylor & Francis
Nalidixic acid is a bacterial DNA gyrase inhibitor and the first member of the synthetic
quinolone antibiotics. It is used in the treatment of various infectious diseases like urinary …

Chebulinic and chebulagic acid binding with serum proteins: biophysical and molecular docking approach

DP Yeggoni, M Meti… - Journal of Biomolecular …, 2023 - Taylor & Francis
Chebulinic acid (CHN) and chebulagic acid (CHG) have been known for centuries for their
anti-cancer, anti-diabetes, HIV and anti-inflammatory properties. In this study, the interaction …

Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches

K Azeem, M Ahmed, A Uddin, S Singh, R Patel… - …, 2023 - Wiley Online Library
This study performed a comparative investigation to explore the interaction mechanisms
between two potential antimalarial compounds, JMI 346 and JMI 105, and human serum …

Purification and Characterization of a Novel Thermostable Papain Inhibitor from Moringa oleifera with Antimicrobial and Anticoagulant Properties

J Cotabarren, S Claver, JA Payrol, J Garcia-Pardo… - Pharmaceutics, 2021 - mdpi.com
Plant cystatins (or phytocystatins) comprise a large superfamily of natural bioactive small
proteins that typically act as protein inhibitors of papain-like cysteine proteases. In this …

Biophysical insights into the binding characteristics of bovine serum albumin with dipyridamole and the influence of molecular interaction with β cyclodextrin

S Afrin, Y Rahman, M Alhaji Isa, S Ahmed… - Journal of …, 2020 - Taylor & Francis
The binding characteristic of anti-platelet drug dipyridamole has been investigated with a
transport protein, serum albumin. A multi-spectroscopic approach has been employed, and …

[PDF][PDF] Structural and biochemical characterization of phytocystatin 6 as a legumain inhibitor from Arabidopsis thaliana and insights into its oligomerization behavior …

NP Santos, D Elfriede - eplus.uni-salzburg.at
Legumains are key molecular players of land plants by acting in a plethora of physiological
processes [4-7]. They are cysteine proteases synthesized as zymogens that undergo pH …