[HTML][HTML] Effects of early life stress on the developing basolateral amygdala-prefrontal cortex circuit: the emerging role of local inhibition and perineuronal nets
A Guadagno, C Belliveau, N Mechawar… - Frontiers in human …, 2021 - frontiersin.org
The links between early life stress (ELS) and the emergence of psychopathology such as
increased anxiety and depression are now well established, although the specific …
increased anxiety and depression are now well established, although the specific …
Using epigenetic clocks to characterize biological aging in studies of children and childhood exposures: A systematic review
RJ Musci, RS Raghunathan, SB Johnson, L Klein… - Prevention …, 2023 - Springer
Biological age, measured via epigenetic clocks, offers a unique and useful tool for
prevention scientists to explore the short-and long-term implications of age deviations for …
prevention scientists to explore the short-and long-term implications of age deviations for …
Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks
Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …
experience of childhood adversity was associated with epigenetic age acceleration in mid …
Father's care uniquely influences male neurodevelopment
JS Danoff, EN Ramos, TD Hinton… - Proceedings of the …, 2023 - National Acad Sciences
Mammalian infants depend on parental care for survival, with numerous consequences for
their behavioral development. We investigated the epigenetic and neurodevelopmental …
their behavioral development. We investigated the epigenetic and neurodevelopmental …
The role of adolescent lifestyle habits in biological aging: A prospective twin study
Background: Adolescence is a stage of fast growth and development. Exposures during
puberty can have long-term effects on health in later life. This study aims to investigate the …
puberty can have long-term effects on health in later life. This study aims to investigate the …
[HTML][HTML] Accelerated epigenetic aging mediates link between adverse childhood experiences and depressive symptoms in older adults: Results from the Health and …
Adverse childhood experiences (ACEs) increase risk for depression at subsequent ages
and have been linked to accelerated biological aging. We hypothesize that accelerated …
and have been linked to accelerated biological aging. We hypothesize that accelerated …
The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)
Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …
[HTML][HTML] Dimensions of childhood adversity differentially affect biological aging in major depression
Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …
health disorders in adulthood that may be mediated, in part, via the effects of such …
[HTML][HTML] The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure
F Dammering, J Martins, K Dittrich, D Czamara… - Neurobiology of …, 2021 - Elsevier
Background Studies reporting accelerated ageing in children with affective disorders or
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
[HTML][HTML] Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders
N Yusupov, L Dieckmann, M Erhart, S Sauer… - …, 2023 - nature.com
Different psychiatric disorders as well as exposure to adverse life events have individually
been associated with multiple age-related diseases and mortality. Age acceleration in …
been associated with multiple age-related diseases and mortality. Age acceleration in …