[HTML][HTML] Psychological and biological mechanisms linking trauma with cardiovascular disease risk
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and
experiences of psychological trauma have been associated with subsequent CVD onset …
experiences of psychological trauma have been associated with subsequent CVD onset …
The cutting edge of epigenetic clocks: In search of mechanisms linking aging and mental health
Individuals with psychiatric disorders are at increased risk of age-related diseases and early
mortality. Recent studies demonstrate that this link between mental health and aging is …
mortality. Recent studies demonstrate that this link between mental health and aging is …
Association of adverse childhood experiences with accelerated epigenetic aging in midlife
Importance Adverse childhood experiences (ACEs) are associated with the risk of poorer
health, and identifying molecular mechanisms may lay the foundation for health promotion in …
health, and identifying molecular mechanisms may lay the foundation for health promotion in …
Stressful life events and accelerated biological aging over time in youths
Experiencing adversity in childhood and adolescence, including stressful life events (SLEs),
may accelerate the pace of development, leading to adverse mental and physical health …
may accelerate the pace of development, leading to adverse mental and physical health …
[HTML][HTML] Dimensions of childhood adversity differentially affect biological aging in major depression
Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …
health disorders in adulthood that may be mediated, in part, via the effects of such …
Associations of early-life adversity with later-life epigenetic aging profiles in the multi-ethnic study of atherosclerosis
LL Schmitz, E Duffie, W Zhao, SM Ratliff… - American Journal of …, 2023 - academic.oup.com
Epigenetic biomarkers of accelerated aging have been widely used to predict disease risk
and may enhance our understanding of biological mechanisms between early-life adversity …
and may enhance our understanding of biological mechanisms between early-life adversity …
Epigenetic aging and PTSD outcomes in the immediate aftermath of trauma
BackgroundPsychological trauma exposure and posttraumatic stress disorder (PTSD) have
been associated with advanced epigenetic age. However, whether epigenetic aging …
been associated with advanced epigenetic age. However, whether epigenetic aging …
Geroscience-Centric Perspective for Geriatric Psychiatry: integrating aging biology with geriatric mental health research
The geroscience hypothesis asserts that physiological aging is caused by a small number of
biological pathways. Despite the explosion of geroscience research over the past couple of …
biological pathways. Despite the explosion of geroscience research over the past couple of …
The Impact of Childhood Mental Health and Substance Use on Methylation Aging Into Adulthood
SL Clark, EW McGinnis, M Zhao, L Xie… - Journal of the American …, 2023 - Elsevier
Objective To test whether childhood mental health symptoms, substance use, and early
adversity accelerate the rate of DNA methylation (DNAm) aging from adolescence to …
adversity accelerate the rate of DNA methylation (DNAm) aging from adolescence to …
[HTML][HTML] Lingering effects of early institutional rearing and cytomegalovirus infection on the natural killer cell repertoire of adopted adolescents
Adversity during infancy can affect neurobehavioral development and perturb the maturation
of physiological systems. Dysregulated immune and inflammatory responses contribute to …
of physiological systems. Dysregulated immune and inflammatory responses contribute to …