Circulating tumor DNA methylation: a promising clinical tool for cancer diagnosis and management

B Wang, M Wang, Y Lin, J Zhao, H Gu… - Clinical Chemistry and …, 2024 - degruyter.com
Cancer continues to pose significant challenges to the medical community. Early detection,
accurate molecular profiling, and adequate assessment of treatment response are critical …

Cell-free DNA methylation patterns in aging and their association with inflamm-aging

SJ Li, X Gao, ZH Wang, J Li, LT Zeng, YM Dang… - …, 2024 - Taylor & Francis
Aim: Liquid biopsies analyzing cell-free DNA (cfDNA) methylation in plasma offer a
noninvasive diagnostic for diseases, with the potential of aging biomarkers underexplored …

Chromatin-and nucleosome-associated features in liquid biopsy: implications for cancer biomarker discovery

L Penny, SC Main, SD De Michino… - Biochemistry and Cell …, 2024 - cdnsciencepub.com
Cell-free DNA (cfDNA) from the bloodstream has been studied for cancer biomarker
discovery, and chromatin-derived epigenetic features have come into the spotlight for their …

Cancer risk and mutational patterns following organ transplantation

Y Shen, D Lian, K Shi, Y Gao, X Hu, K Yu… - Frontiers in Cell and …, 2022 - frontiersin.org
The rapid development of medical technology and widespread application of
immunosuppressive drugs have improved the success rate of organ transplantation …

[HTML][HTML] Circulating tumor DNA in liquid biopsy: Current diagnostic limitation

SC Liu - World Journal of Gastroenterology, 2024 - ncbi.nlm.nih.gov
With the rapid development of science and technology, cell-free DNA (cfDNA) is rapidly
becoming an important biomarker for tumor diagnosis, monitoring and prognosis, and this …

Real‐world application of a fast stool DNA test for colorectal cancer screening in primary screening positive population

Y Zhu, G Zhao, W Ma, X Chen, X Chen, D Li… - Cancer …, 2023 - Wiley Online Library
Background Stool DNA test has been emerged as an effective noninvasive method for
colorectal cancer (CRC) screening, but the real‐world performance of stool DNA test in …

ZFHX3 methylation in peripheral blood monocytes as a potential biomarker for pancreatic cancer detection

Y Li, Z Fan, Y Meng, J Yang, P Li, S Liu, C Pang, L Du… - Pancreatology, 2024 - Elsevier
Background Pancreatic ductal adenocarcinoma (PDAC) is the digestive malignancy with
poor prognosis, and there is still a lack of effective diagnostic biomarkers. Objective We …

LINE-1 Methylation Status in Canine Splenic Hemangiosarcoma Tissue and Cell-Free DNA

H Sato, KI Watanabe, Y Kobayashi, M Tomihari… - Animals, 2023 - mdpi.com
Simple Summary In dogs, hemangiosarcoma is the most common cancer of the spleen.
Although early diagnosis is effective for tumor control, benign and other malignant tumors …

[HTML][HTML] Genome-wide methylation analysis of circulating tumor DNA: A new biomarker for recurrent glioblastom

L Dai, Z Liu, Y Zhu, L Ma - Heliyon, 2023 - cell.com
Background Glioblastoma (GBM) is a malignant tumor with a short survival and poor
prognosis and a lack of clinically validated biomarkers for diagnosis and prognosis. Methods …

Clinical Application of Different Liquid Biopsy Components in Hepatocellular Carcinoma

J Xu, Y Zhao, Z Chen, L Wei - Journal of Personalized Medicine, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer, usually
occurring in the background of chronic liver disease. HCC lethality rate is in the third highest …