The most well-studied epigenetic marker in humans is the 5-methyl modification of cytosine
in DNA, which has great potential as a disease biomarker in liquid biopsies of cell-free DNA …

Background The expression of microRNAs (miRNAs) in the serum of B-cell acute
lymphoblastic leukemia (B-ALL) patients is abnormal. Nevertheless, the underlying …

Lung cancer is a leading cause of cancer-related deaths worldwide, with a low 5-year
survival rate due in part to a lack of clinically useful biomarkers. Recent studies have …

Aim: To evaluate the value of combined detection of plasma cfDNA concentration and
integrity in the early diagnosis of NSCLC. Methods: Real-time fluorescence quantitative PCR …

Background Noninvasive diagnostic markers that are capable of distinguishing patients with
colorectal cancer (CRC) from healthy individuals or patients with other cancer types are …

Background: Oral squamous cell carcinoma (OSCC) is a highly aggressive malignancy that
is characterized by early distant metastasis and poor prognosis. DNA methylation plays an …

Roche's AVENIO ctDNA analysis kits and bioinformatics analysis (the AVENIO system) are
accessible to all NGS laboratories. We have developed an approach, namely the Sec-Seq …

Programmed cell death-1 (PD-1), also known as CD279, is expressed in a variety of immune
cells, including peripheral activated T cells, B cells, and monocytes (Nishimura et al., 1996; …

Periodontitis, a common inflammatory disease affecting the periodontal tissue, poses
diagnostic and management challenges. Conventional methods are not capable of …

背景与目的: 胃癌是中国常见的恶性肿瘤之一, 胃癌诊疗过程中仍缺乏高特异性,
高灵敏度的生物标志物. 甲基化的Septin9 基因(methylated Septin9 gene, mSEPT9) …