[HTML][HTML] Cancer detection and classification by CpG island hypermethylation signatures in plasma cell-free DNA

J Huang, AC Soupir, BD Schlick, M Teng, IH Sahin… - Cancers, 2021 - mdpi.com
Simple Summary The detection of DNA methylation changes in blood has emerged as a
promising approach for cancer diagnosis and management. Our group has previously …

[HTML][HTML] DNA Methylation Biomarkers as Prediction Tools for Therapeutic Response and Prognosis in Intermediate-Stage Hepatocellular Carcinoma

CY Lu, CY Hsiao, PJ Peng, SC Huang, MR Chuang… - Cancers, 2023 - mdpi.com
Simple Summary Patients with hepatocellular carcinoma are often monitored using serum
markers such as alfa-fetoprotein. However, serum markers are not always accurate in …

[HTML][HTML] Hierarchical classification-based pan-cancer methylation analysis to classify primary cancer

Y Yang, Q Zeng, G Liu, S Zheng, T Luo, Y Guo… - BMC …, 2023 - Springer
Hierarchical classification offers a more specific categorization of data and breaks down
large classification problems into subproblems, providing improved prediction accuracy and …

Predictive value of early kinetics of ctDNA combined with cfDNA and serum CEA for EGFR‐TKI treatment in advanced non‐small cell lung cancer

J Zheng, Y Wang, C Hu, M Zhu, J Ii, C Lin, C Lu… - Thoracic …, 2022 - Wiley Online Library
Abstract Background Circulating tumor DNA (ctDNA) has made a breakthrough as an early
biomarker in operable early‐stage cancer patients. However, the function of ctDNA …

[HTML][HTML] Liquid biopsy in T-cell lymphoma: biomarker detection techniques and clinical application

Z Huang, Y Fu, H Yang, Y Zhou, M Shi, Q Li, W Liu… - Molecular Cancer, 2024 - Springer
T-cell lymphoma is a highly invasive tumor with significant heterogeneity. Invasive tissue
biopsy is the gold standard for acquiring molecular data and categorizing lymphoma …

Risk scoring based on DNA methylation-driven related DEGs for colorectal cancer prognosis with systematic insights

Z Liu, I Georgakopoulos-Soares, N Ahituv, KC Wong - Life Sciences, 2023 - Elsevier
Colorectal cancer is a common malignant tumor of the digestive tract. Despite advances in
diagnostic techniques and medications. Its prognosis remains challenging. DNA methylation …

Mutation profiles in circulating cell‐free DNA predict acquired resistance to olaparib in high‐grade serous ovarian carcinoma

D Hu, E Guo, B Yang, X Qin, Y Fu, J Fan… - Cancer …, 2022 - Wiley Online Library
Although resistance to poly (ADP‐ribose) polymerase inhibitors (PARPi) has gradually
become a major challenge in the maintenance therapy for high‐grade serous ovarian …

MIR145 Core Promoter Methylation in Pretreatment Cell-Free DNA: A Liquid Biopsy Tool for Muscle-Invasive Bladder Cancer Treatment Outcome

KM Pilala, G Kotronopoulos, P Levis… - JCO Precision …, 2024 - ascopubs.org
PURPOSE The lack of personalized management of bladder cancer (BlCa) results in
patients' lifelong post-treatment monitoring with invasive interventions, underlying the urgent …

Methylated ccfDNA from plasma biomarkers of Alzheimer's disease using targeted bisulfite sequencing

J Guemri, M Pierre-Jean, S Brohard, N Oussada… - …, 2022 - Future Medicine
Aim: Noninvasive biomarkers such as methylated ccfDNA from plasma could help to support
the diagnosis of Alzheimer's disease (AD). Methods: A targeted sequencing protocol was …

[HTML][HTML] Waiting for the “liquid revolution” in the adjuvant treatment of colon cancer patients: A review of ongoing trials

V Conca, P Ciracì, C Boccaccio, A Minelli… - Cancer Treatment …, 2024 - Elsevier
Since colon cancer has a high rate of shedding of tumour fragments into the blood, several
research efforts are now focused on the investigation of the minimal residual disease …