Enhancing the cancer metastasis diagnosis: Ultrasensitive nano sensors exploiting Cancer stem cell associated DNA methylation as a liquid biopsy marker

S Ganesh, S Premachandran… - Sensors and Actuators B …, 2024 - Elsevier
Cancer metastasis presents a significant clinical challenge due to its impact on patient
survival rates. Early detection of metastasis is pivotal for effective intervention and improved …

Liquid biopsy derived circulating tumor cells and circulating tumor DNA as novel biomarkers in hepatocellular carcinoma

S Temraz, R Nasr, D Mukherji, F Kreidieh… - Expert Review of …, 2022 - Taylor & Francis
Introduction The diagnosis of hepatocellular carcinoma (HCC) is made at a relatively
advanced stage resulting in poor prognosis. Alpha-fetoprotein and liver ultrasound have …

[HTML][HTML] Potential applications of DNA methylation testing technology in female tumors and screening methods

S Peng, X Zhang, Y Wu - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
DNA methylation is a common epigenetic modification, and the current commonly used
methods for DNA methylation detection include methylation-specific PCR, methylation …

[HTML][HTML] Liquid biopsy in T-cell lymphoma: biomarker detection techniques and clinical application

Z Huang, Y Fu, H Yang, Y Zhou, M Shi, Q Li, W Liu… - Molecular Cancer, 2024 - Springer
T-cell lymphoma is a highly invasive tumor with significant heterogeneity. Invasive tissue
biopsy is the gold standard for acquiring molecular data and categorizing lymphoma …

[HTML][HTML] Unlocking the secrets: the power of methylation-based cfDNA detection of tissue damage in organ systems

L Zhang, J Li - Clinical Epigenetics, 2023 - Springer
Background Detecting organ and tissue damage is essential for early diagnosis, treatment
decisions, and monitoring disease progression. Methylation-based assays offer a promising …

[HTML][HTML] DNA Methylation Biomarkers as Prediction Tools for Therapeutic Response and Prognosis in Intermediate-Stage Hepatocellular Carcinoma

CY Lu, CY Hsiao, PJ Peng, SC Huang, MR Chuang… - Cancers, 2023 - mdpi.com
Simple Summary Patients with hepatocellular carcinoma are often monitored using serum
markers such as alfa-fetoprotein. However, serum markers are not always accurate in …

[HTML][HTML] Plasma cell-free DNA as a sensitive biomarker for multi-cancer detection and immunotherapy outcomes prediction

J Xu, H Chen, W Fan, M Qiu, J Feng - Journal of Cancer Research and …, 2024 - Springer
Abstract Background Cell-free DNA (cfDNA) has shown promise in detecting various
cancers, but the diagnostic performance of cfDNA end motifs for multiple cancer types …

Refinement and validation of a comprehensive clinical diagnostic model (GAMAD) based on gender, age, multitarget circulating tumour DNA methylation signature …

T Yang, N Wang, F Wang, H Liu, F Shen, G Lv - BMJ open, 2023 - bmjopen.bmj.com
Introduction Prompt detection of hepatocellular carcinoma (HCC) in patients with chronic
liver diseases is critical for enhancing prognosis. Existing imaging techniques and serum …

[HTML][HTML] Hierarchical classification-based pan-cancer methylation analysis to classify primary cancer

Y Yang, Q Zeng, G Liu, S Zheng, T Luo, Y Guo… - BMC …, 2023 - Springer
Hierarchical classification offers a more specific categorization of data and breaks down
large classification problems into subproblems, providing improved prediction accuracy and …

Minimal residual disease in solid tumors: an overview

Y Ma, J Gan, Y Bai, D Cao, Y Jiao - Frontiers of Medicine, 2023 - Springer
Minimal residual disease (MRD) is termed as the small numbers of remnant tumor cells in a
subset of patients with tumors. Liquid biopsy is increasingly used for the detection of MRD …