Role of blood mSEPT9 in evaluating tumor burden and disease monitoring in colorectal cancer patients

H Jiang, Q Yu, X Chen, C Zhang, J Shen… - Journal of Clinical …, 2021 - Wiley Online Library
Purpose This study aimed to investigate the correlation between mSEPT9 and tumor burden
as well as the role of mSEPT9 in monitoring colorectal cancer (CRC) patients. Methods A …

Liquid biopsies for cancer: From bench to clinic

Z Chen, C Li, Y Zhou, Y Yao, J Liu, M Wu, J Su - MedComm, 2023 - Wiley Online Library
Over the past two decades, liquid biopsy has been increasingly used as a supplement, or
even, a replacement to the traditional biopsy in clinical oncological practice, due to its …

[HTML][HTML] The Diagnostic, Prognostic, and Therapeutic Potential of Cell-Free DNA with a Special Focus on COVID-19 and Other Viral Infections

G Hovhannisyan, T Harutyunyan… - International Journal of …, 2023 - mdpi.com
Cell-free DNA (cfDNA) in human blood serum, urine, and other body fluids recently became
a commonly used diagnostic marker associated with various pathologies. This is because …

[HTML][HTML] Cell-free DNA methylation profiles enable early detection of colorectal and gastric cancer

X Lei, D Zhou, Y Wen, W Sha, J Ma, X Tu… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) and gastric cancer (GC) rank the top five common and lethal
cancers worldwide. Early detection can significantly reduce the mortality of CRC and GC …

[HTML][HTML] Detection of HBV DNA integration in plasma cell-free DNA of different HBV diseases utilizing DNA capture strategy

Z Yang, J Zeng, Y Chen, M Wang, H Luo, AL Huang… - Virologica Sinica, 2024 - Elsevier
The landscape of hepatitis B virus (HBV) integration in the plasma cell-free DNA (cfDNA) of
HBV-infected patients with different stages of liver diseases [chronic hepatitis B (CHB), liver …

[HTML][HTML] Methylomics and cancer: the current state of methylation profiling and marker development for clinical care

C Liu, H Tang, N Hu, T Li - Cancer Cell International, 2023 - Springer
Epigenetic modifications have long been recognized as an essential level in transcriptional
regulation linking behavior and environmental conditions or stimuli with biological …

Peripheral CD4+ T cells correlate with response and survival in patients with advanced non-small cell lung cancer receiving chemo-immunotherapy

X Yang, Q Li, T Zeng - Frontiers in Immunology, 2024 - frontiersin.org
Background The aim of the present study was to explore the potential of peripheral immune
cells in predicting the response and prognosis of patients with advanced non-small cell lung …

[HTML][HTML] Clinical Evidence of Circulating Tumor DNA Application in Aggressive Breast Cancer

B El Hejjioui, L Bouguenouch, MA Melhouf, H El Mouhi… - Diagnostics, 2023 - mdpi.com
Breast cancer is clinically and biologically heterogeneous and is classified into different
subtypes according to the molecular landscape of the tumor. Triple-negative breast cancer is …

[HTML][HTML] Circulating tumor DNA methylation: a promising clinical tool for cancer diagnosis and management

B Wang, M Wang, Y Lin, J Zhao, H Gu… - Clinical Chemistry and …, 2024 - degruyter.com
Cancer continues to pose significant challenges to the medical community. Early detection,
accurate molecular profiling, and adequate assessment of treatment response are critical …

Noninvasive discrimination of benign and malignant breast lesions using genome-wide nucleosome profiles of plasma cell-free DNA

BW Han, GX Cai, Q Liu, X Yang, ZW Guo, LM Huang… - Clinica Chimica …, 2021 - Elsevier
Background Breast malignancy is the most frequently diagnosed malignancy in women
worldwide, and the diagnosis relies on invasive examinations. However, most clinical breast …