Epigenetic age prediction

DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

DNA methylation networks underlying mammalian traits

A Haghani, CZ Li, TR Robeck, J Zhang, AT Lu… - Science, 2023 - science.org
Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …

Epigenetic predictors of maximum lifespan and other life history traits in mammals

CZ Li, A Haghani, TR Robeck, D Villar, AT Lu, J Zhang… - BioRxiv, 2021 - biorxiv.org
Maximum lifespan of a species is the oldest that individuals can survive, reflecting the
genetic limit of longevity in an ideal environment. Here we report methylation-based models …