Biological age (BA) is a common model to evaluate the function of aging individuals as it
may provide a more accurate measure of the extent of human aging than chronological age …

Background: Measures to quantify changes in the pace of biological aging in response to
intervention are needed to evaluate geroprotective interventions for humans. Previously, we …

The aging process is characterized by the presence of high interindividual variation between
individuals of the same chronical age prompting a search for biomarkers that capture this …

Abstract Theory predicts that biological processes of aging may contribute to poor mental
health in late life. To test this hypothesis, we evaluated prospective associations between …

Human ageing is a complex, multifactorial process characterised by physiological damage,
increased risk of age-related diseases and inevitable functional deterioration. As the …

Sleep has been associated with aging and relevant health outcomes, but the causal
relationship remains inconclusive. In this study, we investigated the associations of sleep …

Attaining personalized healthy aging requires accurate monitoring of physiological changes
and identifying subclinical markers that predict accelerated or delayed aging. Classic …

Depression and anxiety are common and often comorbid mental health disorders that
represent risk factors for aging-related conditions. Brain aging has shown to be more …

The exposome, the environmental complement of the genome, is an omics level
characterization of an individual's exposures. There is growing interest in uncovering the …

Epigenetic age (EA) is an emerging DNA methylation-based biomarker of biological aging,
but whether EA is causally associated with short-term PM2. 5 exposure remains unknown …