Histomorphology has been a mainstay of cancer diagnosis in anatomic pathology for many
years. DNA methylation profiling is an additional emerging tool that will serve as an adjunct …

Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and
transcriptomic heterogeneity. Subtypes based upon predominant transcription factor …

Tissue differences are one of the largest contributors to variability in the human DNA
methylome. Despite the tissue-specific nature of DNA methylation, the inaccessibility of …

Long-term exposure to air pollution has been associated with several adverse health effects
including cardiovascular, respiratory diseases and cancers. However, underlying molecular …

Camels bear unique genotypes and phenotypes for adaptation in their environment, and as
such could be very useful in the weather extremes accelerated by global climate change …

Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

Abstract Gene—environment (G× E) interactions have largely been regarded as the root of
many complex disorders, including several psychiatric disorders. In this regard, it has been …

In recent years, numerous studies of gene regulation mechanisms have emerged in
neuroscience. Epigenetic modifications, described as heritable but reversible changes …

Body fluid identification in crime scene investigations aids in reconstruction of crime scenes.
Several studies have identified and reported differentially methylated sites (DMSs) and …