Following its transcription, RNA can be modified by> 170 chemically distinct types of
modifications—the epitranscriptome. In recent years, there have been substantial efforts to …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Chemical modifications on mRNA represent a critical layer of gene expression regulation.
Research in this area has continued to accelerate over the last decade, as more …

RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …

Specific chemical modifications of biological molecules are an efficient way of regulating
molecular function, and a plethora of downstream signalling pathways are influenced by the …

Cancer cells selectively promote translation of specific oncogenic transcripts to facilitate
cancer survival and progression, but the underlying mechanisms are poorly understood …

Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …

Many studies have highlighted the importance of the tight regulation of mRNA stability in the
control of gene expression. mRNA stability largely depends on the mRNA nucleotide …

Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

To this date, over 100 different types of RNA modification have been identified. Methylation
of different RNA species has emerged as a critical regulator of transcript expression. RNA …