[HTML][HTML] Opportunities for artificial intelligence in advancing precision medicine

FV Filipp - Current genetic medicine reports, 2019 - Springer
Abstract Purpose of Review We critically evaluate the future potential of machine learning
(ML), deep learning (DL), and artificial intelligence (AI) in precision medicine. The goal of …

[HTML][HTML] Identification and validation of neurotrophic factor-related gene signatures in glioblastoma and Parkinson's disease

S Zhao, H Chi, Q Yang, S Chen, C Wu, G Lai… - Frontiers in …, 2023 - frontiersin.org
Background Glioblastoma multiforme (GBM) is the most common cancer of the central
nervous system, while Parkinson's disease (PD) is a degenerative neurological condition …

High social status males experience accelerated epigenetic aging in wild baboons

JA Anderson, RA Johnston, AJ Lea, FA Campos… - Elife, 2021 - elifesciences.org
Aging, for virtually all life, is inescapable. However, within populations, biological aging rates
vary. Understanding sources of variation in this process is central to understanding the …

Spatial inequalities of COVID-19 mortality rate in relation to socioeconomic and environmental factors across England

Y Sun, X Hu, J Xie - Science of the total environment, 2021 - Elsevier
In this study, we aimed to examine spatial inequalities of COVID-19 mortality rate in relation
to spatial inequalities of socioeconomic and environmental factors across England …

[HTML][HTML] Identification of cuproptosis-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognosis model in breast cancer

Z Li, H Zhang, X Wang, Q Wang, J Xue, Y Shi… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is now the most frequent and lethal cancer among women. Cuproptosis
is a newly identified programmed cell death process that has been connected to tumor …

[HTML][HTML] Characterization of interplay between autophagy and ferroptosis and their synergistical roles on manipulating immunological tumor microenvironment in …

L Chen, X Niu, X Qiao, S Liu, H Ma, X Shi… - Frontiers in …, 2022 - frontiersin.org
Objective Squamous cell carcinomas (SCCs) with shared etiology, histological
characteristics, and certain risk factors represent the most common solid cancers. This study …

[HTML][HTML] Machine learning-based characterization of cuprotosis-related biomarkers and immune infiltration in Parkinson's disease

S Zhao, L Zhang, W Ji, Y Shi, G Lai, H Chi… - Frontiers in …, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a neurodegenerative disease commonly seen in
the elderly. On the other hand, cuprotosis is a new copper-dependent type of cell death that …

[HTML][HTML] Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network …

Y Liu, Z Yin, Y Wang, H Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Thyroid carcinoma (THCA), the most common endocrine neoplasm, typically
exhibits an indolent behavior. However, in some instances, lymph node metastasis (LNM) …

[HTML][HTML] Identification of disulfidptosis related subtypes, characterization of tumor microenvironment infiltration, and development of DRG prognostic prediction model …

K Xu, Y Zhang, Z Yan, Y Wang, Y Li, Q Qiu… - Frontiers in …, 2023 - frontiersin.org
Disulfidptosis is a newly discovered mode of cell death induced by disulfide stress.
However, the prognostic value of disulfidptosis-related genes (DRGs) in renal cell …

[HTML][HTML] Identification of immune microenvironment subtypes and signature genes for Alzheimer's disease diagnosis and risk prediction based on explainable …

Y Lai, P Lin, F Lin, M Chen, C Lin, X Lin, L Wu… - Frontiers in …, 2022 - frontiersin.org
Background Using interpretable machine learning, we sought to define the immune
microenvironment subtypes and distinctive genes in AD. Methods ssGSEA, LASSO …