Backgrounds As a systemic skeletal dysfunction, osteoporosis (OP) is characterized by low
bone mass and bone microarchitectural damage. The global incidences of OP are high …

Objective: Experimental and clinical evidence suggests that atherosclerosis is a chronic
inflammatory disease. Our study was conducted for uncovering the roles of immune …

Background: Glioma is the most common primary intracranial tumor, accounting for the vast
majority of intracranial malignant tumors. Aberrant expression of RNA: 5-methylcytosine …

Background: Mitophagy is closely related to cancer initiation and progression. However,
heterogeneity with reference to mitophagy remains unexplored in pancreatic …

Introduction Sepsis is the leading cause of death in intensive care units and is characterized
by multiple organ failure, including dysfunction of the immune system. In the present study …

Background Ferroptosis, an iron-dependent manner of lipid peroxidative cell death, has
recently been reported to be strongly associated with rheumatoid arthritis (RA). Targeted …

Objectives: We aim to identify the breast cancer (BC) subtype clusters and the crucial gene
classifier prognostic signatures by integrating genomic analysis with the tumor immune …

Biological age captures physiological deterioration better than chronological age and is
amenable to interventions. Blood-based biomarkers have been identified as suitable …

Robust biomarkers of chronological age have been developed in humans and model
mammalian species such as rats and mice using DNA methylation data. The concept of …

Resilience can be viewed as trajectory of stable good mental health or the quick recovery of
mental health during or after stressor exposure. Resilience factors (RFs) are psychological …