[HTML][HTML] Gene regulation in regeneration after acute kidney injury
JA Beamish, JA Watts, GR Dressler - Journal of Biological Chemistry, 2024 - jbc.org
Acute kidney injury (AKI) is a common condition associated with significant morbidity,
mortality, and cost. Injured kidney tissue can regenerate after many forms of AKI. However …
mortality, and cost. Injured kidney tissue can regenerate after many forms of AKI. However …
[HTML][HTML] Single-cell analysis provides new insights into the roles of tertiary lymphoid structures and immune cell infiltration in kidney injury and chronic kidney disease
T Yoshikawa, M Yanagita - The American Journal of Pathology, 2024 - Elsevier
Chronic kidney disease (CKD) is a global health concern with high morbidity and mortality.
Acute kidney injury (AKI) is a pivotal risk factor for the progression of CKD, and the rate of …
Acute kidney injury (AKI) is a pivotal risk factor for the progression of CKD, and the rate of …
[HTML][HTML] Chromatin conformation and histone modification profiling across human kidney anatomic regions
H Li, D Li, BD Humphreys - Scientific data, 2024 - nature.com
The three major anatomic regions of the human kidney include the cortex, medulla and
papilla, with different functions and vulnerabilities to kidney diseases. Epigenetic …
papilla, with different functions and vulnerabilities to kidney diseases. Epigenetic …
[HTML][HTML] Spatially resolved metabolomic dataset of distinct human kidney anatomic regions
H Li, BD Humphreys - Data in Brief, 2024 - Elsevier
Cortex, medulla and papilla are three major human kidney anatomic structures and they
harbour unique metabolic functions, but the underlying metabolomic profiles are largely …
harbour unique metabolic functions, but the underlying metabolomic profiles are largely …
[HTML][HTML] Protocol for multimodal profiling of human kidneys with simultaneous high-throughput ATAC and RNA expression with sequencing
H Li, BD Humphreys - STAR protocols, 2024 - Elsevier
Simultaneous high-throughput ATAC and RNA expression with sequencing (SHARE-seq)
profiles transcriptomics and chromatin accessibility in the same cells at high throughput …
profiles transcriptomics and chromatin accessibility in the same cells at high throughput …
Using organoid xenograft model of PKD to validate novel pathological pathways revealed by single cell analysis
T Zhang - 2024 - dr.ntu.edu.sg
PKD is a major global health concern, contributing significantly to end-stage renal disease.
Current therapeutic challenges in PKD stem from its complex pathogenesis, requiring …
Current therapeutic challenges in PKD stem from its complex pathogenesis, requiring …