Retroviruses
H Varmus - Science, 1988 - science.org
First brought to scientific attention as infectious cancer-causing agents nearly 80 years ago,
retroviruses are popular in contemporary biology for many reasons.(i) The virus life cycle …
retroviruses are popular in contemporary biology for many reasons.(i) The virus life cycle …
Transcription factor control of virulence in phytopathogenic fungi
E John, KB Singh, RP Oliver… - Molecular Plant …, 2021 - Wiley Online Library
Plant‐pathogenic fungi are a significant threat to economic and food security worldwide.
Novel protection strategies are required and therefore it is critical we understand the …
Novel protection strategies are required and therefore it is critical we understand the …
[HTML][HTML] DNA-binding specificities of human transcription factors
Although the proteins that read the gene regulatory code, transcription factors (TFs), have
been largely identified, it is not well known which sequences TFs can recognize. We have …
been largely identified, it is not well known which sequences TFs can recognize. We have …
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins
WH Landschulz, PF Johnson, SL McKnight - Science, 1988 - science.org
A 30-amino-acid segment of C/EBP, a newly discovered enhancer binding protein, shares
notable sequence similarity with a segment of the cellular Myc transforming protein. Display …
notable sequence similarity with a segment of the cellular Myc transforming protein. Display …
IκB: a specific inhibitor of the NF-κB transcription factor
PA Baeuerle, D Baltimore - Science, 1988 - science.org
In cells that do not express immunoglobulin kappa light chain genes, the kappa enhancer
binding protein NF-κB is found in cytosolic fractions and exhibits DNA binding activity only in …
binding protein NF-κB is found in cytosolic fractions and exhibits DNA binding activity only in …
Conservation of transcription factor binding specificities across 600 million years of bilateria evolution
Divergent morphology of species has largely been ascribed to genetic differences in the
tissue-specific expression of proteins, which could be achieved by divergence in cis …
tissue-specific expression of proteins, which could be achieved by divergence in cis …
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α helices: crystal structure of the protein-DNA complex
The yeast transcriptional activator GCN4 is 1 of over 30 identified eukaryotic proteins
containing the basic region leucine zipper (bZIP) DNA-binding motif. We have determined …
containing the basic region leucine zipper (bZIP) DNA-binding motif. We have determined …
Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element
C Norman, M Runswick, R Pollock, R Treisman - Cell, 1988 - cell.com
The serum response element (SRE) is a sequence required for transient transcriptional
activation of genes in response to growth factors. We have isolated cDNA clones encoding …
activation of genes in response to growth factors. We have isolated cDNA clones encoding …
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
XJ Yang, VV Ogryzko, J Nishikawa, BH Howard… - Nature, 1996 - nature.com
The adenoviral oncoprotein E1A induces progression through the cell cycle by binding to
the products of the p300/CBP and retinoblastoma gene families. A new cellular p300/CBP …
the products of the p300/CBP and retinoblastoma gene families. A new cellular p300/CBP …
c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities
TD Halazonetis, K Georgopoulos, ME Greenberg… - Cell, 1988 - cell.com
The c-jun and c-fos proto-oncogenes encode proteins that form a complex which regulates
transcription from promoters containing AP-1 activation elements. c&n has specific DNA …
transcription from promoters containing AP-1 activation elements. c&n has specific DNA …