Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Importance Genetic factors increase risk of dementia, but the extent to which this can be
offset by lifestyle factors is unknown. Objective To investigate whether a healthy lifestyle is …

Background Alcohol use has been identified as a risk factor for dementia and cognitive
decline. However, some patterns of drinking have been associated with beneficial effects …

Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Objective To examine the association between alcohol consumption and risk of dementia.
Design Prospective cohort study. Setting Civil service departments in London (Whitehall II …

Background Infections have been hypothesised to increase the risk of dementia. Existing
studies have included a narrow range of infectious diseases, relied on short follow-up …

Neurodegenerative diseases are characterized by the progressive functional loss of
neurons in the brain, causing cognitive impairment and motoneuron disability. Although …

Importance The impact of serial changes in alcohol consumption on dementia risk has rarely
been investigated to date. Objective To investigate the association of comprehensive …