The genomes of virtually all organisms contain repetitive sequences that are generated by
the activity of transposable elements (transposons). Transposons are mobile genetic …

Endogenous cytoplasmic DNA (cytoDNA) species are emerging as key mediators of
inflammation in diverse physiological and pathological contexts. Although the role of …

Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

Mammals differ more than 100-fold in maximum lifespan. Here, we conducted comparative
transcriptomics on 26 species with diverse lifespans. We identified thousands of genes with …

Following the spread of the SARS-CoV-2 infection and coronavirus disease 2019 (COVID-
19) to a global pandemic, concerns have arisen for the disease impact in at-risk populations …

Emerging infectious diseases, especially if caused by bat-borne viruses, significantly affect
public health and the global economy. There is an urgent need to understand the …

Abstract Comprising more than 1,400 species, bats possess adaptations unique among
mammals including powered flight, unexpected longevity, and extraordinary immunity. Some …

This Lilliput explores the current epidemiological and virological arguments for a zoonotic
origin of the COVID‐19 pandemic. While the role of bats, pangolins and racoon dogs as viral …

Disproportionately high incidence and mortality of respiratory infection such as influenza A
virus (IAV) and SARS‐CoV‐2 have been evidenced in the elderly, but the role and the …

Fighting infectious diseases, particularly viral infections, is a demanding task for human
health. Targeting the pathogens or targeting the host are different strategies, but with an …