Impact of COVID-19 in the mental health in elderly: psychological and biological updates

RE Grolli, MED Mingoti, AG Bertollo, AR Luzardo… - Molecular …, 2021 - Springer
Since December 2019, the world has been experiencing the challenge of facing coronavirus
disease-19 (COVID-19), a severe infectious disease caused by the new coronavirus, SARS …

[HTML][HTML] Infections in the elderly critically-ill patients

M Esme, A Topeli, BB Yavuz, M Akova - Frontiers in medicine, 2019 - frontiersin.org
Infections are leading causes of morbidity and mortality in the advanced aged. Various
factors including immunosenescens, comorbid chronic diseases, and alterations in normal …

Optimal allocation of the limited COVID-19 vaccine supply in South Korea

E Shim - Journal of clinical medicine, 2021 - mdpi.com
Initial supply of the coronavirus disease (COVID-19) vaccine may be limited, necessitating
its effective use. Herein, an age-structured model of COVID-19 spread in South Korea is …

Sustaining efficient immune functions with regular physical exercise in the COVID‐19 era and beyond

GE Furtado, RV Letieri, A Caldo‐Silva… - European Journal of …, 2021 - Wiley Online Library
The new coronavirus (SARS‐CoV‐2) appearance in Wuhan, China, did rise the new virus
disease (COVID‐19), which spread globally in a short time, leading the World Health …

[HTML][HTML] Aging and options to halt declining immunity to virus infections

MÁ Palacios-Pedrero, ADME Osterhaus… - Frontiers in …, 2021 - frontiersin.org
Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …

[HTML][HTML] What should be the baseline when calculating excess mortality? New approaches suggest that we have underestimated the impact of the COVID-19 …

VM Shkolnikov, I Klimkin, M McKee, DA Jdanov… - SSM-population …, 2022 - Elsevier
Excess mortality has been used to measure the impact of COVID-19 over time and across
countries. But what baseline should be chosen? We propose two novel approaches: an …

Immunosenescence and altered vaccine efficiency in older subjects: A myth difficult to change

T Fulop, A Larbi, G Pawelec, AA Cohen, G Provost… - Vaccines, 2022 - mdpi.com
Organismal ageing is associated with many physiological changes, including differences in
the immune system of most animals. These differences are often considered to be a key …

[HTML][HTML] Who and when to vaccinate against influenza

P Buchy, S Badur - International Journal of Infectious Diseases, 2020 - Elsevier
Known since Hippocrates and of continuing public health importance, influenza remains a
major cause of morbidity and mortality worldwide, and large segments of the human …

[HTML][HTML] Safety and immunogenicity of high-dose quadrivalent influenza vaccine in adults≥ 65 years of age: A phase 3 randomized clinical trial

LJ Chang, Y Meng, H Janosczyk, V Landolfi, HK Talbot… - Vaccine, 2019 - Elsevier
Background A high-dose, split-virion inactivated trivalent influenza vaccine (IIV3-HD;
Fluzone® High-Dose, Sanofi Pasteur) is available for adults≥ 65 years of age. This study …

The impact of immuno-aging on SARS-CoV-2 vaccine development

J Connors, MR Bell, J Marcy, M Kutzler, EK Haddad - Geroscience, 2021 - Springer
The SARS-CoV-2 pandemic has almost 56 million confirmed cases resulting in over 1.3
million deaths as of November 2020. This infection has proved more deadly to older adults …