Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …

Microglia represent a specialized population of macrophages-like cells in the central
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …

Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …

Aging is characterized by a morpho-functional adaptation, variably affecting major
physiological systems, depending on a complex interaction between genetic, environmental …

Background Infections have been hypothesised to increase the risk of dementia. Existing
studies have included a narrow range of infectious diseases, relied on short follow-up …

Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving …

The main discussion above of the novel pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and …