[HTML][HTML] Potential and challenges of specifically isolating extracellular vesicles from heterogeneous populations

S Allelein, P Medina-Perez, ALH Lopes, S Rau… - Scientific reports, 2021 - nature.com
Extracellular vesicles (EVs) have attracted interest due to their ability to provide diagnostic
information from liquid biopsies. Cells constantly release vesicles divers in size, content and …

[HTML][HTML] Current status of circulating tumor cells, circulating tumor DNA, and exosomes in breast cancer liquid biopsies

M Tellez-Gabriel, E Knutsen, M Perander - International Journal of …, 2020 - mdpi.com
Breast cancer is the most common cancer among women worldwide. Although the five-, ten-
and fifteen-year survival rates are good for breast cancer patients diagnosed with early …

Predictive biomarkers for personalized medicine in breast cancer

S Rodrigues-Ferreira, C Nahmias - Cancer Letters, 2022 - Elsevier
Breast cancer is one of the most frequent malignancies among women worldwide. Based on
clinical and molecular features of breast tumors, patients are treated with chemotherapy …

[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …

Integrated approaches for precision oncology in colorectal cancer: The more you know, the better

P Andrei, P Battuello, G Grasso, E Rovera… - Seminars in cancer …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the most common human malignancies accounting for
approximately 10% of worldwide cancer incidence and mortality. While early-stage CRC is …

[HTML][HTML] Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors

I Heidrich, B Deitert, S Werner, K Pantel - Cancer and Metastasis Reviews, 2023 - Springer
Cancer is one of the three leading causes of death worldwide. Even after successful therapy
and achieving remission, the risk of relapse often remains. In this context, dormant residual …

Circulating tumor cells in the early detection of human cancers

Z Feng, Y Feng, N Wang - Handbook of Cancer and Immunology, 2022 - Springer
Cancer is considered as the leading cause of death and the major barrier of longevity
globally. The high mortality of cancer is due to the malignant spread. However, if the disease …

Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment

M Filipska, R Rosell - Molecular Oncology, 2021 - Wiley Online Library
Over the past decade, substantial developments have been made in the detection of
circulating tumor DNA (ctDNA)—cell‐free DNA (cfDNA) fragments released into the …

Droplet microfluidics for CTC-based liquid biopsy: a review

L Jiang, H Yang, W Cheng, Z Ni, N Xiang - Analyst, 2023 - pubs.rsc.org
Circulating tumor cells (CTCs) are important biomarkers of liquid biopsy. The number and
heterogeneity of CTCs play an important role in cancer diagnosis and personalized …

[HTML][HTML] Accelerating the development and validation of liquid biopsy for early cancer screening and treatment tailoring

D Horgan, T Čufer, F Gatto, I Lugowska, D Verbanac… - Healthcare, 2022 - mdpi.com
Liquid biopsy (LB) is a minimally invasive method which aims to detect circulating tumor-
derived components in body fluids. It provides an alternative to current cancer screening …