Breast cancer biomarker profiling predominantly relies on tissue testing (surgical and/or
biopsy samples). However, the field of liquid biopsy, particularly the analysis of circulating …

The advancements in the detection and characterization of circulating tumor DNA (ctDNA)
have revolutionized precision medicine and are likely to transform standard clinical practice …

Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Exosomal microRNA (miRNA) in plasma and urine has attracted attention as a novel
diagnostic tool for pathological conditions. However, the mechanisms of miRNA dynamics in …

Simple Summary The choice of first-line regimen represents a critical step in the therapeutic
road for patients with metastatic colorectal cancer (mCRC) because the response to first-line …

Introduction: Previous publications have shown that STIM1, ORAI1, and KDM2B, are
implicated in Ca2+ signaling and are highly expressed in various cancer subtypes including …

Childhood cancer is the leading cause of nonaccidental death in children and adolescents.
Over the past 50 years, development of novel therapies and improvements in supportive …

Alzheimer's disease (AD) is the most common neurodegenerative disease and affects
persons of all races, ethnic groups, and sexes. The disease is characterized by neuronal …

The discovery and clinical validation of biomarkers predictive of the response of non-
squamous non-small-cell lung carcinomas (NS-NSCLC) to therapeutic strategies continue to …

Prostate cancer is characterized by several genetic alterations which could impact prognosis
and therapeutic decisions in the advanced disease. Tissue biopsy is still considered the …