[HTML][HTML] Copper homeostasis and copper-induced cell death: novel targeting for intervention in the pathogenesis of vascular aging

Z Chen, Y Li, X Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Copper-induced cell death, also known as cuproptosis, is distinct from other types of cell
death such as apoptosis, necrosis, and ferroptosis. It can trigger the accumulation of lethal …

[HTML][HTML] Copper metabolism and cuproptosis: molecular mechanisms and therapeutic perspectives in neurodegenerative diseases

X Ban, H Wan, X Wan, Y Tan, X Hu, H Ban… - Current medical …, 2024 - Springer
Copper is an essential trace element, and plays a vital role in numerous physiological
processes within the human body. During normal metabolism, the human body maintains …

[HTML][HTML] A novel Alzheimer's disease prognostic signature: identification and analysis of glutamine metabolism genes in immunogenicity and immunotherapy efficacy

Z Wu, P Liu, B Huang, S Deng, Z Song, X Huang… - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is characterized as a distinct onset and progression of cognitive
and functional decline associated with age, as well as a specific neuropathology. It has been …

[HTML][HTML] Bioinformatics prediction and experimental validation identify a novel cuproptosis-related gene signature in human synovial inflammation during osteoarthritis …

W Wang, Z Chen, Y Hua - Biomolecules, 2023 - mdpi.com
Osteoarthritis (OA) is the one of most common joint diseases worldwide. Cuproptosis, which
had been discovered lately, is a novel form of cell death induced by copper. Our purpose is …

[HTML][HTML] Role of cuproptosis in understanding diseases

S Cao, Q Wang, Z Sun, Y Zhang, Q Liu, Q Huang… - Human Cell, 2023 - Springer
Cell death is involved in a wide range of physiological and pathological processes.
Recently, the term “cuproptosis” was coined to describe a novel type of cell death. This type …

[HTML][HTML] Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics …

G Ouyang, Z Wu, Z Liu, G Pan, Y Wang, J Liu… - Frontiers in …, 2023 - frontiersin.org
Background and aims Cuproptosis has been identified as a key player in the development of
several diseases. In this study, we investigate the potential role of cuproptosis-related genes …

[HTML][HTML] A Concise Review on Oxidative Stress-Mediated Ferroptosis and Cuproptosis in Alzheimer's Disease

X Huang - Cells, 2023 - mdpi.com
Alzheimer's disease (AD), which was first identified more than a century ago, has become a
pandemic that exacts enormous social burden and economic tolls as no measure of …

[HTML][HTML] Identification and validation of BCL6 and VEGFA as biomarkers and ageing patterns correlating with immune infiltrates in OA progression

Z Chen, W Wang, Y Hua - Scientific Reports, 2023 - nature.com
Osteoarthritis (OA), the most common type of arthritis, is a complex biological response
caused by cartilage wear and synovial inflammation that links biomechanics and …

[HTML][HTML] Identification of immune infiltration and cuproptosis-related molecular clusters in tuberculosis

S Li, Q Long, L Nong, Y Zheng, X Meng… - Frontiers in …, 2023 - frontiersin.org
Background Tuberculosis (TB) is an infectious disease caused by Mycobacterium
tuberculosis (Mtb) infection. Cuproptosis is a novel cell death mechanism correlated with …

[HTML][HTML] Identification of copper death-associated molecular clusters and immunological profiles in rheumatoid arthritis

Y Zhou, X Li, L Ng, Q Zhao, W Guo, J Hu… - Frontiers in …, 2023 - frontiersin.org
Objective An analysis of the relationship between rheumatoid arthritis (RA) and copper
death-related genes (CRG) was explored based on the GEO dataset. Methods Based on the …