Repetitive elements (REs), such as transposable elements (TEs) and satellites, comprise
much of the genome. Here, we review how TEs and (peri) centromeric satellite DNA may …

The vertebrate genome is under constant threat of invasion by genetic parasites. Whether
the host can immediately recognize and respond to invading elements has been unclear …

Numerous novel adaptations characterise the radiation of notothenioids, the dominant fish
group in the freezing seas of the Southern Ocean. To improve understanding of the …

The mobility of transposable elements (TEs) contributes to evolution of genomes. Their
uncontrolled activity causes genomic instability; therefore, expression of TEs is silenced by …

Cys2-His2 zinc finger genes (ZNFs) form the largest family of transcription factors in
metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and …

Ongoing host–pathogen interactions can trigger a coevolutionary arms race, while genetic
diversity within the host can facilitate its adaptation to pathogens. Here, we used the …

Trimethylation of histone H3 lysine 9 (H3K9me3) is crucial for the regulation of gene
repression and heterochromatin formation, cell-fate determination and organismal …

Canonical Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) act as
major repressors of transposable elements (TEs) via the KRAB-mediated recruitment of the …

The HUSH complex recognizes and silences foreign DNA such as viruses, transposons, and
transgenes without prior exposure to its targets. Here, we show that endogenous targets of …

Endogenous retroviruses (ERVs) are evolutionary remnants of retroviral infections in which
the viral genome became embedded as a dormant regulatory element within the host …