A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

It is widely reported that the mitochondrial membrane potential,∆ Ψm, is reduced in aging
animals. It was recently suggested that the lower∆ Ψm in aged animals modulates …

This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …

Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …

Recently, attention has been drawn to the adverse outcomes of N-(1, 3-Dimethylbutyl)-N′-
phenyl-p-phenylenediamine quinone (6PPDQ) on human health, but its cardiac toxicity has …

Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

Platycodi radix is a widely used herbal medicine that contains numerous phytochemicals
beneficial to health. The health and biological benefits of P. radix have been found across …

Pineal melatonin and the cortisol awakening response (CAR) are integral aspects of the
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …

Oxidative stress arises from an imbalance between reactive oxidants and the antioxidant
defense system in cells. This article outlines the mechanisms and effects of oxidative stress …