Enhancing head and neck tumor management with artificial intelligence: Integration and perspectives

NN Zhong, HQ Wang, XY Huang, ZZ Li, LM Cao… - Seminars in Cancer …, 2023 - Elsevier
Head and neck tumors (HNTs) constitute a multifaceted ensemble of pathologies that
primarily involve regions such as the oral cavity, pharynx, and nasal cavity. The intricate …

Strategies to reduce the risks of mRNA drug and vaccine toxicity

D Bitounis, E Jacquinet, MA Rogers… - Nature Reviews Drug …, 2024 - nature.com
Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …

Technology-enabled great leap in deciphering plant genomes

L Xie, X Gong, K Yang, Y Huang, S Zhang, L Shen… - Nature Plants, 2024 - nature.com
Plant genomes provide essential and vital basic resources for studying many aspects of
plant biology and applications (for example, breeding). From 2000 to 2020, 1,144 genomes …

Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics

A Barulin, DD Nguyen, Y Kim, C Ko, I Kim - ACS Photonics, 2024 - ACS Publications
Metasurfaces have revolutionized optical biosensing and diagnostic assays due to their
sensitivity, compactness, and label-free operation. However, metasurface applications in …

Enablers and challenges of spatial omics, a melting pot of technologies

T Alexandrov, J Saez‐Rodriguez… - Molecular Systems …, 2023 - embopress.org
Spatial omics has emerged as a rapidly growing and fruitful field with hundreds of
publications presenting novel methods for obtaining spatially resolved information for any …

Integrating population genetics, stem cell biology and cellular genomics to study complex human diseases

N Farbehi, DR Neavin, ASE Cuomo, L Studer… - Nature Genetics, 2024 - nature.com
Human pluripotent stem (hPS) cells can, in theory, be differentiated into any cell type,
making them a powerful in vitro model for human biology. Recent technological advances …

The Role of G Protein–Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes

MJ Varney, JL Benovic - Pharmacological Reviews, 2024 - ASPET
Type 2 diabetes (T2D) mellitus has emerged as a major global health concern that has
accelerated in recent years due to poor diet and lifestyle. Afflicted individuals have high …

[HTML][HTML] Spatial transcriptomic technologies

TY Chen, L You, JAU Hardillo, MP Chien - Cells, 2023 - mdpi.com
Spatial transcriptomic technologies enable measurement of expression levels of genes
systematically throughout tissue space, deepening our understanding of cellular …

Myasthenia gravis: the changing treatment landscape in the era of molecular therapies

R Iorio - Nature Reviews Neurology, 2024 - nature.com
Myasthenia gravis (MG) is an autoimmune disorder that affects the neuromuscular junction,
leading to muscle weakness and fatigue. MG is caused by antibodies against the …

[HTML][HTML] Opportunities and tradeoffs in single-cell transcriptomic technologies

MI Conte, A Fuentes-Trillo, CD Conde - Trends in Genetics, 2024 - cell.com
Recent technological and algorithmic advances enable single-cell transcriptomic analysis
with remarkable depth and breadth. Nonetheless, a persistent challenge is the compromise …