Complex post-traumatic stress disorder

A Maercker, M Cloitre, R Bachem, YR Schlumpf… - The lancet, 2022 - thelancet.com
Complex post-traumatic stress disorder (complex PTSD) is a severe mental disorder that
emerges in response to traumatic life events. Complex PTSD is characterised by three core …

Early adversity and critical periods: neurodevelopmental consequences of violating the expectable environment

CA Nelson, LJ Gabard-Durnam - Trends in neurosciences, 2020 - cell.com
It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …

Adverse childhood experiences and the consequences on neurobiological, psychosocial, and somatic conditions across the lifespan

JI Herzog, C Schmahl - Frontiers in psychiatry, 2018 - frontiersin.org
Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

Racial disparities in adversity during childhood and the false appearance of race-related differences in brain structure

NM Dumornay, LAM Lebois… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Black Americans in the United States are disproportionately exposed to childhood
adversity compared with White Americans. Such disparities may contribute to race-related …

Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

Burden of environmental adversity associated with psychopathology, maturation, and brain behavior parameters in youths

RE Gur, TM Moore, AFG Rosen, R Barzilay… - JAMA …, 2019 - jamanetwork.com
Importance Low socioeconomic status (L-SES) and the experience of traumatic stressful
events (TSEs) are environmental factors implicated in behavioral deficits, abnormalities in …

Structural and functional brain abnormalities associated with exposure to different childhood trauma subtypes: A systematic review of neuroimaging findings

LLM Cassiers, BGC Sabbe, L Schmaal… - Frontiers in …, 2018 - frontiersin.org
Background: Childhood trauma subtypes sexual abuse, physical abuse, emotional
maltreatment, and neglect may have differential effects on the brain that persist into …

The complex neurobiology of resilient functioning after childhood maltreatment

K Ioannidis, AD Askelund, RA Kievit, AL Van Harmelen - BMC medicine, 2020 - Springer
Background Childhood maltreatment has been associated with significant impairment in
social, emotional and behavioural functioning later in life. Nevertheless, some individuals …

Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health

CM Heim, S Entringer, C Buss - Psychoneuroendocrinology, 2019 - Elsevier
This review integrates scientific knowledge obtained over the past few decades on the
biological mechanisms that contribute to the profound association between exposure to …

Adverse childhood events and cognitive function among young adults: Prospective results from the national longitudinal study of adolescent to adult health

MAW Hawkins, HM Layman, KT Ganson, J Tabler… - Child Abuse & …, 2021 - Elsevier
Abstract Background Adverse childhood experiences (ACEs) may have lasting impacts on
cognition. Objective To determine if ACE exposure is prospectively associated with cognition …