Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
Advances in the development of new biomarkers for Alzheimer's disease
TO Klyucherev, P Olszewski, AA Shalimova… - Translational …, 2022 - Springer
Alzheimer's disease (AD) is a complex, heterogeneous, progressive disease and is the most
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …
common type of neurodegenerative dementia. The prevalence of AD is expected to increase …
miRTargetLink 2.0—interactive miRNA target gene and target pathway networks
Which genes, gene sets or pathways are regulated by certain miRNAs? Which miRNAs
regulate a particular target gene or target pathway in a certain physiological context …
regulate a particular target gene or target pathway in a certain physiological context …
The miRNA–target interactions: An underestimated intricacy
MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …
cellular regulatory impact is determined not solely by their sheer number, which likely …
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues
Molecular mechanisms of organismal and cell aging remain incompletely understood. We,
therefore, generated a body-wide map of noncoding RNA (ncRNA) expression in aging (16 …
therefore, generated a body-wide map of noncoding RNA (ncRNA) expression in aging (16 …
miEAA 2023: updates, new functional microRNA sets and improved enrichment visualizations
MicroRNAs (miRNAs) are small non-coding RNAs that play a critical role in regulating
diverse biological processes. Extracting functional insights from a list of miRNAs is …
diverse biological processes. Extracting functional insights from a list of miRNAs is …
Role of miRNA dysregulation in sepsis
A Formosa, P Turgeon, CC Dos Santos - Molecular Medicine, 2022 - Springer
Background Sepsis is defined as a state of multisystem organ dysfunction secondary to a
dysregulated host response to infection and causes millions of deaths worldwide annually …
dysregulated host response to infection and causes millions of deaths worldwide annually …
Circulating exosome‐like vesicle and skeletal muscle microRNAs are altered with age and resistance training
D Xhuti, MI Nilsson, K Manta… - The Journal of …, 2023 - Wiley Online Library
The age‐related loss of skeletal muscle mass and functionality, known as sarcopenia, is a
critical risk factor for morbidity and all‐cause mortality. Resistance exercise training (RET) is …
critical risk factor for morbidity and all‐cause mortality. Resistance exercise training (RET) is …
Neuroprotective Effects of Lactobacillus plantarum PS128 in a Mouse Model of Parkinson's Disease: The Role of Gut Microbiota and MicroRNAs
YZ Lee, SH Cheng, MY Chang, YF Lin, CC Wu… - International Journal of …, 2023 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disease characterized by motor deficits
and marked neuroinflammation in various brain regions. The pathophysiology of PD is …
and marked neuroinflammation in various brain regions. The pathophysiology of PD is …
miRNAs as therapeutic tools in Alzheimer's disease
Alzheimer's disease (AD), an age-dependent, progressive neurodegenerative disorder, is
the most common type of dementia, accounting for 50–70% of all dementia cases. Due to …
the most common type of dementia, accounting for 50–70% of all dementia cases. Due to …