The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …

Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Human aging is a multifactorial phenomenon that affects numerous organ systems and
cellular processes, with the immune system being one of the most dysregulated …

As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Background The weathering hypothesis views the elevated rates of illness, disability, and
mortality seen among Black Americans as a physiological response to the structural barriers …

The exposome concept refers to the totality of exposures from a variety of external and
internal sources including chemical agents, biological agents, or radiation, from conception …

Background Despite a clear link between aging and cancer, there has been inconclusive
evidence on how biological age (BA) may be associated with cancer incidence. Methods We …

In animal studies, β-nicotinamide mononucleotide (NMN) supplementation increases
nicotinamide adenine dinucleotide (NAD) concentrations and improves healthspan and …

Telomere length (TL) is associated with several aging-related diseases. Here, we present a
DNA methylation estimator of TL (DNAmTL) based on 140 CpGs. Leukocyte DNAmTL is …

Since the worldwide COVID-19 pandemic was declared a year ago, the search for vaccines
has become the top priority in order to restore normalcy after 2.5 million deaths worldwide …