We investigated the dynamic properties of the organism state fluctuations along individual
aging trajectories in a large longitudinal database of CBC measurements from a consumer …

Immune system is a versatile and dynamic body organ which offers survival and endurance
of human beings in their hostile living environment. However, similar to other cells, immune …

Structural equation modeling (SEM) is a very general and flexible multivariate technique that
allows relationships among variables to be examined. The roots of SEM are in the social …

Species that hibernate generally live longer than would be expected based solely on their
body size. Hibernation is characterized by long periods of metabolic suppression (torpor) …

Aging is the single most important risk factor for diseases that are currently the leading
causes of morbidity and mortality. However, there is considerable inter-individual variability …

Many countries are witnessing a marked increase in longevity and with this increased
lifespan and the desire for healthy ageing, many, however, suffer from the opposite including …

Quantifying biological aging is critical for understanding why aging is the primary driver of
morbidity and mortality and for assessing novel therapies to counter pathological aging. In …

Objective: The objective of this study was to explore the potential correlation between the
composite dietary antioxidant index (CDAI) and biological aging, addressing the insufficient …

Epigenetic mechanisms guiding articular cartilage regeneration and age‐related disease
such as osteoarthritis (OA) are poorly understood. STAT3 is a critical age‐patterned …

Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …