Bioactive compounds and biomedical applications of endophytic fungi: a recent review

AH Hashem, MS Attia, EK Kandil, MM Fawzi… - Microbial Cell …, 2023 - Springer
Human life has been significantly impacted by the creation and spread of novel species of
antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and …

Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

An overview of drug discovery and development

N Berdigaliyev, M Aljofan - Future medicinal chemistry, 2020 - Taylor & Francis
A new medicine will take an average of 10–15 years and more than US $2 billion before it
can reach the pharmacy shelf. Traditionally, drug discovery relied on natural products as the …

The potential use of plant natural products and plant extracts with antioxidant properties for the prevention/treatment of neurodegenerative diseases: in vitro, in vivo …

F Pohl, P Kong Thoo Lin - Molecules, 2018 - mdpi.com
Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

An updated and comprehensive review of the antiviral potential of essential oils and their chemical constituents with special focus on their mechanism of action …

AR Wani, K Yadav, A Khursheed, MA Rather - Microbial Pathogenesis, 2021 - Elsevier
Essential oils and their chemical constituents have been reported with well documented
antimicrobial effects against a range of bacterial, fungal and viral pathogens. By definition …

Ursolic acid and its derivatives as bioactive agents

S Mlala, AO Oyedeji, M Gondwe, OO Oyedeji - Molecules, 2019 - mdpi.com
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and
cardiovascular diseases continue to be threatening and deadly to human kind. Resistance …

Anti-inflammatory and immunomodulatory properties of fermented plant foods

R Shahbazi, F Sharifzad, R Bagheri, N Alsadi… - Nutrients, 2021 - mdpi.com
Fermented plant foods are gaining wide interest worldwide as healthy foods due to their
unique sensory features and their health-promoting potentials, such as antiobesity …

Effects of apigenin on RBL-2H3, RAW264. 7, and HaCaT cells: anti-allergic, anti-inflammatory, and skin-protective activities

CH Park, SY Min, HW Yu, K Kim, S Kim, HJ Lee… - International Journal of …, 2020 - mdpi.com
Apigenin (4′, 5, 7-trihydroxyflavone, flavonoid) is a phenolic compound that is known to
reduce the risk of chronic disease owing to its low toxicity. The first study on apigenin …

The circular chemistry conceptual framework: A way forward to sustainability in industry 4.0

SV Mohan, R Katakojwala - Current Opinion in Green and Sustainable …, 2021 - Elsevier
In the framework of sustainability, low-carbon chemistry is presuming importance and
consequently, infusion of circular economy (CE) concept will play a vital role to encompass …

Identification of natural inhibitors against prime targets of SARS-CoV-2 using molecular docking, molecular dynamics simulation and MM-PBSA approaches

A Sharma, J Vora, D Patel, S Sinha… - Journal of …, 2022 - Taylor & Francis
The recently emerged COVID-19 has been declared a pandemic by the World Health
Organization as to date; no therapeutic drug/vaccine is available for the treatment. Due to …