Age-related white matter (WM) microstructure maturation and decline occur throughout the
human lifespan with a unique trajectory in the brain, complementing the process of gray …

Normative models of brain metrics based on large populations are extremely valuable for
detecting brain abnormalities in patients with dementia, psychiatric, or developmental …

Human brain morphology undergoes complex changes over the lifespan. Despite recent
progress in tracking brain development via normative models, current knowledge of …

The value of normative models in research and clinical practice relies on their robustness
and a systematic comparison of different modelling algorithms and parameters; however …

Background: Normative brain volume reports (NBVR) are becoming more available in the
work-up of patients with suspected dementia disorders, potentially leveraging the value of …

Abstract Background Alzheimer's Disease (AD), identified as the most common type of
dementia, presents considerable heterogeneity in clinical manifestations. Early intervention …

Copy number variations (CNVs) are genetic variants that can have a substantial influence
on neurodevelopment, neuropsychiatric traits, and morphometric brain changes, yet their …

Background Clinical forecasting models have potential to optimize treatment and improve
outcomes in psychosis, but predicting long-term outcomes is challenging and long-term …

Background. Inter-individual variability in neurobiological and clinical characteristics in
mental illness is often overlooked by classical group-mean case-control studies. Studies …

In the past, the cerebellum has been best known for its crucial role in motor function.
However, increasingly more findings highlight the importance of cerebellar contributions in …