Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

[HTML][HTML] Associations of essential trace elements with epigenetic aging indicators and the potential mediating role of inflammation

X Cheng, Y Wei, R Wang, C Jia, Z Zhang, J An, W Li… - Redox Biology, 2023 - Elsevier
Abstract Background Essential trace elements (ETEs) play essential roles in vital functions,
but their effects on epigenetic aging remain poorly understood. Objectives This study aimed …

[HTML][HTML] Is exposure to pesticides associated with biological aging? A systematic review and meta-analysis

S Zuo, V Sasitharan, GL Di Tanna, JM Vonk… - Ageing Research …, 2024 - Elsevier
Objective Exposure to pesticides is a risk factor for various diseases, yet its association with
biological aging remains unclear. We aimed to systematically investigate the relationship …

Educational mobility, pace of aging, and lifespan among participants in the Framingham heart study

GHJ Graf, AE Aiello, A Caspi, M Kothari, H Liu… - JAMA Network …, 2024 - jamanetwork.com
Importance People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …

[HTML][HTML] Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults

YE Willems, A deSteiguer, PT Tanksley, L Vinnik… - Clinical …, 2024 - Springer
Self-control is a personality dimension that is associated with better physical health and a
longer lifespan. Here, we examined (1) whether self-control is associated with buccal and …

Body size, diet quality, and epigenetic aging: cross-sectional and longitudinal analyses

DL Li, AM Hodge, L Cribb, MC Southey… - The Journals of …, 2024 - academic.oup.com
Epigenetic age is an emerging marker of health that is highly predictive of disease and
mortality risk. There is a lack of evidence on whether lifestyle changes are associated with …

Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell‐type deconvolution applied to human blood epigenetic clocks

Z Zhang, SR Reynolds, HG Stolrow, JQ Chen… - Aging …, 2024 - Wiley Online Library
Aging is a significant risk factor for various human disorders, and DNA methylation clocks
have emerged as powerful tools for estimating biological age and predicting health‐related …

[HTML][HTML] Exposure to ambient temperature and heat index in relation to DNA methylation age: a population-based study in Taiwan

KC Chiu, MS Hsieh, YT Huang, CY Liu - Environment International, 2024 - Elsevier
Background Climate change caused an increase in ambient temperature in the past
decades. Exposure to high ambient temperature could result in biological aging, but relevant …

Accelerated pace of aging in schizophrenia: five case-control studies

A Caspi, G Shireby, J Mill, TE Moffitt, K Sugden… - Biological …, 2024 - Elsevier
Background Schizophrenia is associated with increased risk of developing multiple aging-
related diseases, including metabolic, respiratory, and cardiovascular diseases, and …

Occupational characteristics and epigenetic aging among older adults in the United States

T Andrasfay, E Crimmins - Epigenetics, 2023 - Taylor & Francis
Occupational characteristics have been studied as risk factors for several age-related
diseases and are thought to impact the ageing process, although there has been limited …