The role of pyroptosis and gasdermin family in tumor progression and immune microenvironment
M Li, P Jiang, Y Yang, L Xiong, S Wei, J Wang… - … Hematology & Oncology, 2023 - Springer
Pyroptosis, an inflammatory programmed cell death, distinguishes itself from apoptosis and
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …
Role of gasdermin family proteins in cancers
X Yang, Z Tang - International Journal of Oncology, 2023 - spandidos-publications.com
The gasdermin (GSDM) family comprises six proteins, including GSDMA‑GSDME and
Pejvakin. Most of these proteins have a crucial role in inducing pyroptosis; in particular …
Pejvakin. Most of these proteins have a crucial role in inducing pyroptosis; in particular …
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma
Pyroptosis and necroptosis are two recently identified forms of immunogenic cell death in
the tumor microenvironment (TME), indicating a crucial involvement in tumor metastasis …
the tumor microenvironment (TME), indicating a crucial involvement in tumor metastasis …
miR‐149‐3p Is a Potential Prognosis Biomarker and Correlated with Immune Infiltrates in Uterine Corpus Endometrial Carcinoma
X Lu, L Jing, S Liu, H Wang… - International Journal of …, 2022 - Wiley Online Library
Background. Endocrine disruption is an important factor in the development of endometrial
cancer. Expression of miR‐149‐3p is observed in some cancer types, while its role in …
cancer. Expression of miR‐149‐3p is observed in some cancer types, while its role in …
A systematic pan-cancer analysis of the gasdermin (GSDM) family of genes and their correlation with prognosis, the tumor microenvironment, and drug sensitivity
Y Zheng, D Yuan, F Zhang, R Tang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Pyroptosis is a programmed cell death process mediated by the gasdermin
(GSDM) protein. However, limited research has been conducted to comprehensively …
(GSDM) protein. However, limited research has been conducted to comprehensively …
[HTML][HTML] Construction of T cell exhaustion model for predicting survival and immunotherapy effect of bladder cancer based on WGCNA
Y Xue, G Zhao, X Pu, F Jiao - Frontiers in Oncology, 2023 - frontiersin.org
The prognosis of bladder cancer (BLCA) and response to immune checkpoint inhibitors
(ICIs) are determined by multiple factors. Existed biomarkers for predicting the effect of …
(ICIs) are determined by multiple factors. Existed biomarkers for predicting the effect of …
[HTML][HTML] Molecular mechanisms of pyroptosis and its role in anti-tumor immunity
H Huang, Y Weng, W Tian, X Lin, J Chen… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Pyroptosis is a form of cell death that is characterized by the destruction of the cell, and it has
implications in both the immune system and cancer immunotherapy. The gasdermin family is …
implications in both the immune system and cancer immunotherapy. The gasdermin family is …
[HTML][HTML] Systematic pan-cancer analysis identifies gasdermin B as an immunological and prognostic biomarker for kidney renal clear cell carcinoma
X Liu, F Xie, J Ding, S Li, J Li - Frontiers in Oncology, 2023 - frontiersin.org
Gasdermins (GSDMs)-mediated cell lytic death plays an essential role in immunity and
tumorigenesis. Despite the association of gasdermin B (GSDMB) with the tumorigenesis of …
tumorigenesis. Despite the association of gasdermin B (GSDMB) with the tumorigenesis of …
[HTML][HTML] Identification and verification of the pyroptosis-related prognostic signature and its associated regulatory axis in bladder cancer
Y Tu, X Ding, Z Mao - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Background: Pyroptosis is an inflammatory form of cell death triggered by certain
inflammasomes. Accumulating studies have shown the involvement of pyroptosis in the …
inflammasomes. Accumulating studies have shown the involvement of pyroptosis in the …
[HTML][HTML] Gasdermins: a dual role in pyroptosis and tumor immunity
J Yang, J Jiang - Frontiers in Immunology, 2024 - frontiersin.org
The gasdermin (GSDM) protein family plays a pivotal role in pyroptosis, a process critical to
the body's immune response, particularly in combatting bacterial infections, impeding tumor …
the body's immune response, particularly in combatting bacterial infections, impeding tumor …