[PDF][PDF] LincRNA-p21 suppresses target mRNA translation

JH Yoon, K Abdelmohsen, S Srikantan, X Yang… - Molecular cell, 2012 - cell.com
Mammalian long intergenic noncoding RNAs (lincRNAs) are best known for modulating
transcription. Here we report a posttranscriptional function for lincRNA-p21 as a modulator of …

KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3

T Lan, H Li, D Zhang, L Xu, H Liu, X Hao, X Yan… - Molecular cancer, 2019 - Springer
Abstract Background N6-methyladenosine (m6A) modification, the most abundant internal
methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the …

Long non-coding RNAs in the cytoplasm

F Rashid, A Shah, G Shan - Genomics, proteomics and …, 2016 - academic.oup.com
An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic
genome are important regulators in different aspects of cellular events. Cytoplasm is the …

GC content shapes mRNA storage and decay in human cells

M Courel, Y Clément, C Bossevain, D Foretek… - Elife, 2019 - elifesciences.org
mRNA translation and decay appear often intimately linked although the rules of this
interplay are poorly understood. In this study, we combined our recent P-body transcriptome …

[HTML][HTML] Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits

Y Xue, K Ouyang, J Huang, Y Zhou, H Ouyang, H Li… - Cell, 2013 - cell.com
The induction of pluripotency or trans-differentiation of one cell type to another can be
accomplished with cell-lineage-specific transcription factors. Here, we report that repression …

Regulation of cytoplasmic mRNA decay

DR Schoenberg, LE Maquat - Nature Reviews Genetics, 2012 - nature.com
Discoveries made over the past 20 years highlight the importance of mRNA decay as a
means of modulating gene expression and thereby protein production. Up until recently …

Purification of cross-linked RNA-protein complexes by phenol-toluol extraction

EC Urdaneta, CH Vieira-Vieira, T Hick… - Nature …, 2019 - nature.com
Recent methodological advances allowed the identification of an increasing number of RNA-
binding proteins (RBPs) and their RNA-binding sites. Most of those methods rely, however …

In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates

W Ma, G Zhen, W Xie, C Mayr - Elife, 2021 - elifesciences.org
Liquid-like condensates have been thought to be sphere-like. Recently, various
condensates with filamentous morphology have been observed in cells. One such …

Posttranscriptional upregulation by microRNAs

S Vasudevan - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …

[PDF][PDF] Principles and properties of eukaryotic mRNPs

SF Mitchell, R Parker - Molecular cell, 2014 - cell.com
The proper processing, export, localization, translation, and degradation of mRNAs are
necessary for regulation of gene expression. These processes are controlled by mRNA …