Widespread RNA binding by chromatin-associated proteins
Background Recent evidence suggests that RNA interaction can regulate the activity and
localization of chromatin-associated proteins. However, it is unknown if these observations …
localization of chromatin-associated proteins. However, it is unknown if these observations …
[HTML][HTML] Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis
J Wang, Y Guo, H Chu, Y Guan, J Bi… - International journal of …, 2013 - mdpi.com
The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …
Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer
Y Lan, X Xiao, Z He, Y Luo, C Wu, L Li… - Nucleic acids …, 2018 - academic.oup.com
Overexpressed in colon carcinoma-1 (OCC-1) is one of the earliest annotated long
noncoding RNAs (lncRNAs) in colorectal cancer (CRC); however, its function remains …
noncoding RNAs (lncRNAs) in colorectal cancer (CRC); however, its function remains …
Cytoplasmic Rbfox1 regulates the expression of synaptic and autism-related genes
JA Lee, A Damianov, CH Lin, M Fontes, NN Parikshak… - Neuron, 2016 - cell.com
Human genetic studies have identified the neuronal RNA binding protein, Rbfox1, as a
candidate gene for autism spectrum disorders. While Rbfox1 functions as a splicing …
candidate gene for autism spectrum disorders. While Rbfox1 functions as a splicing …
HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
The identification of sites where RNA-binding proteins (RNABPs) interact with target RNAs
opens the door to understanding the vast complexity of RNA regulation. UV cross-linking …
opens the door to understanding the vast complexity of RNA regulation. UV cross-linking …
PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data
DL Corcoran, S Georgiev, N Mukherjee, E Gottwein… - Genome biology, 2011 - Springer
Crosslinking and immunoprecipitation (CLIP) protocols have made it possible to identify
transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a …
transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a …
RNA-binding protein nucleolin in disease
K Abdelmohsen, M Gorospe - RNA biology, 2012 - Taylor & Francis
Nucleolin is a multifunctional protein localized primarily in the nucleolus, but also found in
the nucleoplasm, cytoplasm and cell membrane. It is involved in several aspects of DNA …
the nucleoplasm, cytoplasm and cell membrane. It is involved in several aspects of DNA …
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance
LIN28 is a conserved RNA-binding protein implicated in pluripotency, reprogramming, and
oncogenesis. It was previously shown to act primarily by blocking let-7 microRNA (miRNA) …
oncogenesis. It was previously shown to act primarily by blocking let-7 microRNA (miRNA) …
Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
F Yang, A Hu, D Li, J Wang, Y Guo, Y Liu, H Li, Y Chen… - Molecular cancer, 2019 - Springer
Abstract Background Circular RNAs (circRNAs), a subclass of non-coding RNAs, play
essential roles in tumorigenesis and aggressiveness. Our previous study has identified that …
essential roles in tumorigenesis and aggressiveness. Our previous study has identified that …