[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

Advances in COVID-19 mRNA vaccine development

E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

C Junqueira, Â Crespo, S Ranjbar, LB De Lacerda… - Nature, 2022 - nature.com
SARS-CoV-2 can cause acute respiratory distress and death in some patients. Although
severe COVID-19 is linked to substantial inflammation, how SARS-CoV-2 triggers …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Discovery of S-217622, a noncovalent oral SARS-CoV-2 3CL protease inhibitor clinical candidate for treating COVID-19

Y Unoh, S Uehara, K Nakahara, H Nobori… - Journal of medicinal …, 2022 - ACS Publications
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths and threatens …

Postacute COVID-19 is characterized by gut viral antigen persistence in inflammatory bowel diseases

A Zollner, R Koch, A Jukic, A Pfister, M Meyer… - Gastroenterology, 2022 - Elsevier
Background & Aims The coronavirus disease 2019 (COVID-19) pandemic has affected
populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19 …

COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

The role of plant‐derived natural antioxidants in reduction of oxidative stress

B Akbari, N Baghaei‐Yazdi, M Bahmaie… - …, 2022 - Wiley Online Library
Free radicals are a group of damaging molecules produced during the normal metabolism of
cells in the human body. Exposure to ultraviolet radiation, cigarette smoking, and other …

Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission

B Pickering, O Lung, F Maguire, P Kruczkiewicz… - Nature …, 2022 - nature.com
Wildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral
variants that can emerge to infect humans. In North America, there is phylogenomic …

Search and sequence analysis tools services from EMBL-EBI in 2022

F Madeira, M Pearce, ARN Tivey… - Nucleic acids …, 2022 - academic.oup.com
The EMBL-EBI search and sequence analysis tools frameworks provide integrated access to
EMBL-EBI's data resources and core bioinformatics analytical tools. EBI Search …