Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …

Antibodies have been used to prevent or treat viral infections since the nineteenth century,
but the full potential to use passive immunization for infectious diseases has yet to be …

Background For most classes of drugs, rapid development of therapeutics to treat emerging
infections is challenged by the timelines needed to identify compounds with the desired …

The search for a universal filovirus vaccine that provides protection against multiple filovirus
species has been prompted by sporadic but highly lethal outbreaks of Ebolavirus and …

The 2014 Ebola virus disease (EVD) outbreak in West Africa and the subsequent outbreaks
of 2018–2020 in Equator and North Kivu provinces of the Democratic Republic of the Congo …

Ebola virus disease (EVD) in humans is associated with four ebolaviruses: Ebola virus
(EBOV), Sudan virus (SUDV), Bundibugyo virus (BDBV), and Taï Forest virus. To date, no …

Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded
RNA viruses that cause severe health effects in humans and non-human primates, including …

The Ebola virus (EBOV) genome encodes a partly conserved 40-residue nonstructural
polypeptide, called the delta peptide, that is produced in abundance during Ebola virus …

Highlights•Principal transmission mode of EBOV is through close contact with contaminated
fluids.•Currently no evidence to suggest aerosol transmission in a natural setting.•West …

We performed whole-genome sequencing with bait enrichment techniques to analyze
Andes virus (ANDV), a cause of human hantavirus pulmonary syndrome. We used …