[HTML][HTML] mRNA vaccines for infectious diseases: principles, delivery and clinical translation

N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …

[HTML][HTML] A guide to vaccinology: from basic principles to new developments

AJ Pollard, EM Bijker - Nature Reviews Immunology, 2021 - nature.com
Immunization is a cornerstone of public health policy and is demonstrably highly cost-
effective when used to protect child health. Although it could be argued that immunology has …

Age-dependent immune response to the Biontech/Pfizer BNT162b2 coronavirus disease 2019 vaccination

L Müller, M Andrée, W Moskorz, I Drexler… - Clinical Infectious …, 2021 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
has led to the development of various vaccines. Real-life data on immune responses elicited …

[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

[HTML][HTML] The aging gut microbiome and its impact on host immunity

N Bosco, M Noti - Genes & Immunity, 2021 - nature.com
The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

COVID-19 infection: implications for perioperative and critical care physicians

JR Greenland, MD Michelow, L Wang, MJ London - Anesthesiology, 2020 - pubs.asahq.org
Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19),
an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome …

The total mass, number, and distribution of immune cells in the human body

R Sender, Y Weiss, Y Navon, I Milo… - Proceedings of the …, 2023 - National Acad Sciences
The immune system is a complex network of cells with critical functions in health and
disease. However, a comprehensive census of the cells comprising the immune system is …

[HTML][HTML] Advances in lipid nanoparticles for mRNA-based cancer immunotherapy

ML Guevara, F Persano, S Persano - Frontiers in chemistry, 2020 - frontiersin.org
Over the past decade, messenger RNA (mRNA) has emerged as potent and flexible platform
for the development of novel effective cancer immunotherapies. Advances in non-viral gene …

[HTML][HTML] An overview of vaccine adjuvants: current evidence and future perspectives

A Facciolà, G Visalli, A Laganà, A Di Pietro - Vaccines, 2022 - mdpi.com
Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

[HTML][HTML] A comprehensive review of mRNA vaccines

V Gote, PK Bolla, N Kommineni, A Butreddy… - International journal of …, 2023 - mdpi.com
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …