Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

The escalating prevalence of metabolic diseases and an aging demographic has been
correlated with a concerning rise in Alzheimer's disease (AD) incidence. This study aimed to …

Traumatic Brain Injury (TBI) is a major cause of disability and mortality, particularly among
the elderly, yet our mechanistic understanding of how age renders the post-traumatic brain …

Abstract Background Gemfibrozil (Gem) is a drug that has been shown to activate PPAR‐α,
a nuclear receptor that plays a key role in regulating lipid metabolism. Gem is used to lower …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder predominantly
affecting the elderly. While conventional pharmacological therapies remain the primary …

Microbial infection as a type of environmental risk factors is considered to be associated with
long-term increased risk of dementia, including Alzheimer's disease (AD). AD is …

Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …

Alzheimer's disease (AD) constitutes a multifactorial neurodegenerative pathology
characterized by cognitive deterioration, personality alterations, and behavioral shifts. The …

In recent years, Clusterin, a glycosylated protein with multiple biological functions, has
attracted extensive research attention. It is closely associated with the physiological and …