Immunoengineering biomaterials for musculoskeletal tissue repair across lifespan

J Han, AN Rindone, JH Elisseeff - Advanced Materials, 2024 - Wiley Online Library
Musculoskeletal diseases and injuries are among the leading causes of pain and morbidity
worldwide. Broad efforts have focused on developing pro‐regenerative biomaterials to treat …

Circulating biomarkers of inflammaging and Alzheimer's disease to track age-related trajectories of dementia: Can we develop a clinically relevant composite …

AM Abbatecola, A Giuliani, L Biscetti, L Scisciola… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a rapidly growing global concern due to a consistent rise of the
prevalence of dementia which is mainly caused by the aging population worldwide. An early …

[HTML][HTML] Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats

Z Kuai, X Chao, Y He, W Ren - Experimental Gerontology, 2023 - Elsevier
Background Our previous studies found that autophagy levels in liver and intestinal
segments of naturally aging rats were downregulated, and the expression of pro …

[HTML][HTML] Evaluation of the Impact of Alternanthera philoxeroides (Mart.) Griseb. Extract on Memory Impairment in D-Galactose-Induced Brain Aging in Mice through Its …

P Aon-Im, O Monthakantirat, S Daodee, Y Chulikhit… - Molecules, 2024 - mdpi.com
Aging is a well-known factor that accelerates brain deterioration, resulting in impaired
learning and memory functions. This current study evaluated the potential of an extract of …

[HTML][HTML] Spreading Senescent Cells' Burden and Emerging Therapeutic Targets for Frailty

S Marcozzi, G Bigossi, ME Giuliani, G Lai, R Giacconi… - Cells, 2023 - mdpi.com
The spreading of senescent cells' burden holds profound implications for frailty, prompting
the exploration of novel therapeutic targets. In this perspective review, we delve into the …

[HTML][HTML] Tracking the evolution of anti-SARS-CoV-2 antibodies and long-term humoral immunity within 2 years after COVID-19 infection

M Movsisyan, N Truzyan, I Kasparova, A Chopikyan… - Scientific Reports, 2024 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that gave rise to
COVID-19 infection produced a worldwide health crisis. The virus can cause a serious or …

Exposure to phthalates and their alternatives in relation to biomarkers of inflammation and oxidative stress in adults: evidence from NHANES 2017–2018

S Jin, S Cui, X Mu, Z Liu, Y Han, T Cui, W Xiong… - … Science and Pollution …, 2023 - Springer
Phthalates and their alternatives are considered significant environmental risk factors that
potentially influence inflammation and oxidative stress. However, their impact on biomarkers …

[HTML][HTML] Ultrasound and neuroinflammation: immune modulation via the heat shock response

GM Seasons, C Pellow, HF Kuipers, GB Pike - Theranostics, 2024 - ncbi.nlm.nih.gov
Current pharmacological therapeutic approaches targeting chronic inflammation exhibit
transient efficacy, often with adverse effects, limiting their widespread use-especially in the …

A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation

MG Pontifex, E Connell, G Le Gall, L Lang… - Gut …, 2024 - Taylor & Francis
The Mediterranean diet (MD) and its bioactive constituents have been advocated for their
neuroprotective properties along with their capacity to affect gut microbiota speciation and …

The Benefits of the Mediterranean Diet on Inflamm-Aging in Childhood Obesity

V Calcaterra, E Verduci, C Milanta, M Agostinelli… - Nutrients, 2024 - mdpi.com
(1) Background: Numerous elements of the Mediterranean diet (MD) have antioxidant and
anti-inflammatory qualities.(2) Methods: We present a narrative review of the potential …